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Gene · 79813

EHMT1: euchromatic histone lysine methyltransferase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EHMT1: euchromatic histone lysine methyltransferase 1. Genes, record 79813. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/79813

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Gene

Symbol
EHMT1
HGNC
Name
euchromatic histone lysine methyltransferase 1
HGNC
NCBI Gene ID
79813
NCBI Gene
HGNC ID
HGNC:24650
HGNC
Ensembl
ENSG00000181090
NCBI Gene
Aliases
EHMT1-IT1, EUHMTASE1, Eu-HMTase1, FLJ12879, FLJ40292, FP13812, GLP, GLP1, KIAA1876, KLEFS1, KMT1D, bA188C12.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H9B1Histone-lysine N-methyltransferase EHMT11,29823Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445352Q9H9B1Espacenet
EP 4641201 A22025-10-2916517Q9H9B1Espacenet
JP 2025147176 A2025-10-064637Q9H9B1Espacenet
JP 2025529142 A2025-09-046244Q9H9B1Espacenet
US 12371689 B22025-07-296244Q9H9B1Espacenet
JP 2025517969 A2025-06-1216517Q9H9B1Espacenet
JP 2025028160 A2025-02-284637Q9H9B1Espacenet
KR 1020250010750 A2025-01-214637Q9H9B1Espacenet
JP 2024109657 A2024-08-144644Q9H9B1Espacenet
US 11920164 B22024-03-05200Q9H9B1Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,962

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEHMT1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant202025
P30CA016086Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant62025
P30DK026687New York Obesity Research Center62025
R01DA007359Molecular Studies of Cocaine Action in Brain62025
R01DK097441Molecular mechanisms of UCP1-independent pathways in metabolic health62025
P01CA125066Discovery of Anticancer Agents of Diverse Natural Origin52025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)52025
P30CA016087Cancer Center Support Grant52025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology52025

1 to 10 of 1,962Source NIH's project files

See all 1,962 nih grants

Papers2,587

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Deep phenotyping of EHMT1 ankyrin repeat domain missense variants in Kleefstra syndrome by multi-tiered structural genomics analyses at atomic resolution.Hum Mol Genet202642804670PubTator, text miningPubMed
TDP-43 dysfunction induces cryptic circular RNAs in ALS/FTD.bioRxiv202642779765PubTator, text miningPubMed
Adjuvant Glucagon-Like Peptide-1 Receptor Agonist Therapy Post-Bariatric Surgery: An Exploratory Single-Institution Analysis.J Surg Res202642767161PubTator, text miningPubMed
Low-dose polysaccharides exert dual redox effects via the ROS-mediated MAPK pathway: Antioxidant alone or pro-oxidant when GLP is combined with doxorubicin in A2780 ovarian cancer cells.Cell Signal202642759906PubTator, text miningPubMed
Association of GLP-1-based therapy with asthma-related outcomes in patients with obesity: a propensity-matched retrospective cohort study.Expert Rev Respir Med202642733229PubTator, text miningPubMed
Combined loss of histone methyltransferases GLP and G9a disrupts neural crest cell fate determination.J Clin Invest202642593859PubTator, text miningPubMed
Tirzepatide Persistence and Associated Changes in Clinical Outcomes in US Adults With Obesity or Overweight: A 6-Month Claims Database Analysis.Diabetes Obes Metab202642575714PubTator, text miningPubMed
Nutritional considerations for glucagon-like peptide-based therapies: An Asian Indian consensus recommendation.Obes Pillars202642529748PubTator, text miningPubMed
A role for EHMT2 in a novel autosomal recessive neurodevelopmental syndrome? A case report.Front Genet202642434347PubTator, text miningPubMed
Epigenomic dysregulation in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: An in silico and in vitro study.Mol Biol Rep202642429854PubTator, text miningPubMed

1 to 10 of 2,587

See all 2,587 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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