Gene · 79840
NHEJ1: non-homologous end joining factor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NHEJ1: non-homologous end joining factor 1. Genes, record 79840. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/79840
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9H9Q4 | Non-homologous end-joining factor 1 | 299 | 27 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55879 | Q9H9Q4 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7357 | Q9H9Q4 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7357 | Q9H9Q4 | Espacenet |
| EP 4464338 A2 | 2024-11-20 | 290 | Q9H9Q4 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1221 | Q9H9Q4 | Espacenet |
| US 11680268 B2 | 2023-06-20 | 290 | Q9H9Q4 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 57560 | Q9H9Q4 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 160531 | Q9H9Q4 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 7464 | Q9H9Q4 | Espacenet |
| US 10746735 B2 | 2020-08-18 | 1221 | Q9H9Q4 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants860
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NHEJ1 papers | Newest fiscal year |
|---|---|---|---|
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 53 | 2025 |
| R35GM118009 | Site-Specific Recombination in Human Health & Disease | 15 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 7 | 2025 |
| R13AI094943 | Annual Primary Immune Deficiency Treatment Consortium (PIDTC) Workshop and Education Day | 6 | 2025 |
| P01AG047200 | Comparative genomics of longevity and Alzheimer's disease | 5 | 2025 |
| P30CA118100 | University of New Mexico Cancer Center Support Grant | 5 | 2025 |
| R01CA097096 | DNA Polymerases in Nonhomologous End Joining | 5 | 2025 |
| R01ES005775 | Oncometabolites, DNA Repair, and Cancer | 5 | 2025 |
1 to 10 of 860Source NIH's project files
See all 860 nih grantsPapers1,354
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Base editing reversal of radiation sensitivity in NHEJ1 immunodeficiency. | J Hum Immun | 2026 | 42690170 | PubTator, text mining | PubMed |
| Successful Therapy of CNS Tuberculosis With Granulomatous Inflammation in Immunodeficiency. | Clin Pediatr (Phila) | 2026 | 42638394 | PubTator, text mining | PubMed |
| Characterization of a Ku-binding motif in the C-terminal region of RAG2. | DNA Repair (Amst) | 2026 | 42585842 | PubTator, text mining | PubMed |
| A NHEJ1 mutator allele influencing germline mutation rates sex-specifically in humans. | Sci Adv | 2026 | 42536752 | PubTator, text mining | PubMed |
| Case Report: A case series of using whole exome sequencing to detect novel variants in Vietnamese patients with inborn errors of immunity. | Front Genet | 2026 | 42283036 | PubTator, text mining | PubMed |
| HSF1 and YTHDC1 enhance DNA repair under heat stress by promoting repair-associated gene expression. | Nucleic Acids Res | 2026 | 42055551 | PubTator, text mining | PubMed |
| Protein arginine methyltransferases in cancer: mechanisms, functions, and therapeutic opportunities. | J Biomed Sci | 2026 | 41928257 | PubTator, text mining | PubMed |
| An Update on Inborn Errors of V(D)J Recombination. | Physiology (Bethesda) | 2026 | 41902554 | PubTator, text mining | PubMed |
| Indel pattern-guided repair mapping reveals genome-wide DNA repair networks in CRISPR/Cas9 editing. | Nucleic Acids Res | 2026 | 41891877 | PubTator, text mining | PubMed |
| Nonhomologous end joining-the importance of end tethering and beyond. | Genes Dev | 2026 | 41871908 | PubTator, text mining | PubMed |
1 to 10 of 1,354
See all 1,354 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/79840
GET https://conductscience.org/api/genes/v1/79840/patents