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Gene · 7994

KAT6A: lysine acetyltransferase 6A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KAT6A: lysine acetyltransferase 6A. Genes, record 7994. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7994

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Gene

Symbol
KAT6A
HGNC
Name
lysine acetyltransferase 6A
HGNC
NCBI Gene ID
7994
NCBI Gene
HGNC ID
HGNC:13013
HGNC
Ensembl
ENSG00000083168
NCBI Gene
Aliases
ARTHS, MOZ, MRD32, MYST-3, MYST3, RUNXBP2, ZC2HC6A, ZNF220
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92794Histone acetyltransferase KAT6A2,00421Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192512Q92794Espacenet
EP 4641201 A22025-10-292102Q92794Espacenet
JP 2025147176 A2025-10-0615194Q92794Espacenet
JP 2025517969 A2025-06-122102Q92794Espacenet
JP 2025517970 A2025-06-122512Q92794Espacenet
JP 2025028160 A2025-02-2815194Q92794Espacenet
KR 1020250010750 A2025-01-2115194Q92794Espacenet
JP 2024109657 A2024-08-1415033Q92794Espacenet
JP 2023549761 A2023-11-29248Q92794Espacenet
EP 4223770 A22023-08-0942Q92794Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,279

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKAT6A papersNewest fiscal year
P30CA008748Cancer Center Support Grant162025
P30CA016672Cancer Center Support Grant102025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias92025
P30CA021765Cancer Center Support Grant (CCSG)72025
R01HD106051Quantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorder72025
P30CA006927Comprehensive Cancer Center Program at Fox Chase52025
P30CA006973Regional Oncology Research Center52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant52025
P50CA217694SPORE in Soft Tissue Sarcoma52025

1 to 10 of 1,279Source NIH's project files

See all 1,279 nih grants

Papers1,720

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
KAT6A inhibitor-loaded and anti-PD-L1-coated manganese metal-organic framework nanoplatform for enhanced colorectal cancer immunotherapy via cGAS-STING activation.Int J Pharm X202642756777PubTator, text miningPubMed
Tandem Double Inversion Resolves the Structural Paradox Underlying Recurrent KAT6A::NCOA2 Fusion in Acute Myeloid Leukemia.Genes Chromosomes Cancer202642704008PubTator, text miningPubMed
KAT6A-inhibitor co-crystal structures: tackling a challenging crystallization target via two alternative approaches.Acta Crystallogr D Struct Biol202642657771PubTator, text miningPubMed
Targeted Degradation of KAT6A: Expanding the Therapeutic Frontier of Epigenetic Drug Discovery.ACS Med Chem Lett202642621538PubTator, text miningPubMed
An Explicit Interaction-Prompted Diffusion Framework for High-Fidelity 3D Molecular Generation.J Am Chem Soc202642619129PubTator, text miningPubMed
Integrated population-based evidence, network toxicology, single-cell profiling, and in vitro studies elucidate mechanisms connecting PAHs to stroke.Ecotoxicol Environ Saf202642594829PubTator, text miningPubMed
Beyond acetylation: Evaluating the emerging biology of lysine acylation.Cell Chem Biol202642586062PubTator, text miningPubMed
OverlappING and DivergING roles of ING4 and ING5 in cancer, differentiation and development.Front Cell Dev Biol202642577687PubTator, text miningPubMed
Expanding the Hematologic Phenotype of Arboleda-Tham Syndrome: A Novel KAT6A Variant Associated With Bone Marrow Failure Requiring Hematopoietic Stem Cell Transplantation.Pediatr Blood Cancer202642479970PubTator, text miningPubMed
Circulating epigenetic and epitranscriptomic biomarkers identify EGFR status, predict TKI response and reveal therapeutic vulnerabilities in NSCLC.Sci Rep202642477403PubTator, text miningPubMed

1 to 10 of 1,720

See all 1,720 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7994

GET https://conductscience.org/api/genes/v1/7994/patents?page=2