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Gene · 8000

PSCA: prostate stem cell antigen

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PSCA: prostate stem cell antigen. Genes, record 8000. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8000

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Gene

Symbol
PSCA
HGNC
Name
prostate stem cell antigen
HGNC
NCBI Gene ID
8000
NCBI Gene
HGNC ID
HGNC:9500
HGNC
Ensembl
ENSG00000167653
NCBI Gene
Aliases
PRO232, lncPSCA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O43653Prostate stem cell antigen1141Ensembl, GeneID, HGNC

Source UniProt

Patents102

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026012855 A2026-01-2731O43653Espacenet
JP 2026004568 A2026-01-1459426O43653Espacenet
EP 4640849 A22025-10-29529O43653Espacenet
EP 4641201 A22025-10-293626O43653Espacenet
JP 2025519096 A2025-06-24529O43653Espacenet
JP 2025517969 A2025-06-123626O43653Espacenet
US 12252547 B22025-03-1820O43653Espacenet
JP 2025024198 A2025-02-1914772O43653Espacenet
EP 4487869 A22025-01-08416O43653Espacenet
EP 4488293 A22025-01-0820O43653Espacenet

1 to 10 of 102

See all 102 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
MK-4721CHEMBL2109548Prostate stem cell antigen inhibitorINHIBITOR

Source ChEMBL

Trials3

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01608711MK-4721PHASE2ClinicalTrials.gov
NCT00902291MK-4721PHASE2ClinicalTrials.gov
NCT00519233MK-4721PHASE1ClinicalTrials.gov

NIH grants938

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePSCA papersNewest fiscal year
P30CA016042Cancer Center Support Grant312025
P30CA008748Cancer Center Support Grant282025
P30CA006973Regional Oncology Research Center102025
P30CA016672Cancer Center Support Grant102025
P30CA033572Cancer Center Support Grant82025
P50CA092629SPORE in Prostate Cancer82025
P50CA097186The Pacific Northwest Prostate Cancer SPORE82025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant72025
P50CA126752SPORE in Lymphoma72025
P30CA016056Roswell Park Cancer Center Support Grant52025

1 to 10 of 938Source NIH's project files

See all 938 nih grants

Papers1,687

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Advances, challenges, and innovative strategies of CAR-T cell therapy in pancreatic cancer.Biomark Res202642681683PubTator, text miningPubMed
Site-Resolved Plasma-Protein Architecture of Infection Susceptibility: A Cis-pQTL Mendelian Randomization and Colocalization Study.Genes (Basel)202642650080PubTator, text miningPubMed
Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes.Lab Invest202642641761PubTator, text miningPubMed
A radiotherapy resistance-related prognostic signature predicts survival and the immune landscape in rectal cancer.Transl Cancer Res202642591449PubTator, text miningPubMed
Shared Genetics of Kidney Function Traits and Bladder Cancer: A Genome-Wide Cross-Trait Analysis.Cancer Med202642470241PubTator, text miningPubMed
Development and internal validation of a risk prediction model for gastric precancerous lesions integrating Helicobacter pylori serologic typing and host susceptibility polymorphisms.Medicine (Baltimore)202642410859PubTator, text miningPubMed
nanoASM: Long-Read Allele-Specific DNA Methylation Profiling Enables Functional Annotation of Regulatory Noncoding Variants in Human Prostate Tissues.bioRxiv202642395488PubTator, text miningPubMed
Integrative analysis of gastric tissue transcriptomes and gastric cancer GWAS implicates candidate susceptibility genes.Am J Hum Genet202642392035PubTator, text miningPubMed
Unveiling the Importance of the Expression of LY6/UPAR Gene Family Members in Urothelial Carcinoma of the Urinary Bladder.Biomedicines202642351767PubTator, text miningPubMed
Establishment and validation of a prognostic model for pancreatic cancer utilizing genes of tumor-associated neutrophils.Discov Oncol202642286393PubTator, text miningPubMed

1 to 10 of 1,687

See all 1,687 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8000

GET https://conductscience.org/api/genes/v1/8000/patents?page=2