ConductScience.org, home

Gene · 80149

ZC3H12A: zinc finger CCCH-type containing 12A

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. ZC3H12A: zinc finger CCCH-type containing 12A. Genes, record 80149. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/80149

On this page

Gene

Symbol
ZC3H12A
HGNC
Name
zinc finger CCCH-type containing 12A
HGNC
NCBI Gene ID
80149
NCBI Gene
HGNC ID
HGNC:26259
HGNC
Ensembl
ENSG00000163874
NCBI Gene
Aliases
FLJ23231, MCPIP, MCPIP-1, MCPIP1, Reg1, Regnase-1, dJ423B22.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q5D1E8Endoribonuclease ZC3H12A5993Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-299472Q5D1E8Espacenet
WO 2025217591 A12025-10-1665Q5D1E8Espacenet
JP 2025147176 A2025-10-0615898Q5D1E8Espacenet
JP 2025524002 A2025-07-2516Q5D1E8Espacenet
JP 2025517969 A2025-06-129472Q5D1E8Espacenet
KR 1020250039465 A2025-03-2016Q5D1E8Espacenet
JP 2025028160 A2025-02-2815898Q5D1E8Espacenet
KR 1020250010750 A2025-01-2115898Q5D1E8Espacenet
JP 2024109657 A2024-08-1415737Q5D1E8Espacenet
JP 2024023699 A2024-02-2116Q5D1E8Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants736

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleZC3H12A papersNewest fiscal year
P30CA016672Cancer Center Support Grant52025
R37DE022550Host and Fungal Regulation of Type 17 Immunity to Oral Candidiasis52025
ZIABC011176Functions of KSHV microRNAs and circular RNAs52025
R01AI140761Transcriptional and metabolic heterogeneity in T cell differentiation42025
R01AI131703Regulation of T cell memory in tissue immunity32025
R37AI105887Metabolic checkpoint in dendritic cell subsets and adaptive immunity32025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center22025
P30CA006973Regional Oncology Research Center22025
P30CA014520UW Comprehensive Cancer Center Support22025
P30CA021765Cancer Center Support Grant (CCSG)22025

1 to 10 of 736Source NIH's project files

See all 736 nih grants

Papers1,426

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The regnase family in autoimmune diseases: a regnase-1-centered perspective on cellular heterogeneity.Mol Biol Rep202642821208PubTator, text miningPubMed
The ribonuclease ZC3H12A stabilizes BRCA1 mRNA in DNA damage response.Redox Biol202642809925PubTator, text miningPubMed
Targeting Regnase-1 in B7-H3-CAR T cells reprograms the tumor microenvironment and enhances antitumor efficacy for osteosarcoma.Cell Rep Med202642641597PubTator, text miningPubMed
RNF213 marks a regulatory T-cell subset associated with ulcerative colitis.Front Immunol202642519321PubTator, text miningPubMed
RNA-Seq Profiling Reveals Transcriptional Changes in Phosphorylation-Site Mutants of Brg1.Genes Cells202642469951PubTator, text miningPubMed
Genomic architecture of IRF4 rearrangements in childhood and adult large B-cell lymphomas.Blood Adv202642466980PubTator, text miningPubMed
Corrigendum to: "The endonuclease MCPIP1 protects against liver cancer development in a sex-dependent manner by modulating β-catenin and CREB1" [JHEP Reports 8 (2026) 101755].JHEP Rep202642418958PubTator, text miningPubMed
Inositol biosynthesis is inversely regulated by glycolytic activity.Biochim Biophys Acta Mol Cell Biol Lipids202642242622PubTator, text miningPubMed
Integrated transcriptomic profiling of programmed cell death patterns unveils macrophage-hepatocyte crosstalk via THBS1-CD47 axis in hepatic ischemia-reperfusion injury.Front Immunol202642238567PubTator, text miningPubMed
High Regnase-1 Expression Is Associated with an Immunosuppressive Tumor Microenvironment and Aggressive Features in Glioma Patients.Cancers (Basel)202642193017PubTator, text miningPubMed

1 to 10 of 1,426

See all 1,426 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/80149

GET https://conductscience.org/api/genes/v1/80149/patents?page=2