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Gene · 80198

Papers1,460

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction: MUS81 participates in the progression of serous ovarian cancer associated with dysfunctional DNA repair system.Front Oncol202642757248PubTator, text miningPubMed
Scutellarin as a specific GEN1 inhibitor synergizes with olaparib to induce synthetic lethality in human tumor cells.Bioorg Chem202642632200PubTator, text miningPubMed
CHK2 regulates MUS81-dependent DSBs in response to replication stress and BRCA2 deficiency.Nucleic Acids Res202642598853PubTator, text miningPubMed
CRISPR Screening Identifies SMARCAL1 and MRN as Modulators of WRN Dependency in MSI-H Colorectal Cancer.Cancer Res202642484294PubTator, text miningPubMed
Author Correction: Epitranscriptomic RNA editing resolves Mus81 DNA repair tradeoffs in heat tolerance and meiosis.Nat Commun202642425981PubTator, text miningPubMed
CIP2A recruits SLX4-MUS81-XPF in mitosis and protects against replication stress.EMBO Rep202642192029PubTator, text miningPubMed
Phosphorylation by CDK1 switches the function of the human SLX4 SAP domain from DNA binding to MUS81 binding.Nucleic Acids Res202642130070PubTator, text miningPubMed
Genome-Scale CRISPR Screens Reveal DNA Repair Dependencies That Sensitize Hepatocellular Carcinoma to Oxaliplatin.Cancers (Basel)202642122158PubTator, text miningPubMed
COSA-1-SLX-4 interaction directly links crossover designation with Holliday junction resolution.Sci Adv202642030394PubTator, text miningPubMed
Distinct mechanisms of replication stress induced by oncogenic RAS and cyclin E1 converge on R-loop-dependent fork reversal.Nat Commun202641932903PubTator, text miningPubMed
ESCO2 Interacts with TRF1/2 and Facilitates Telomere Maintenance.Int J Mol Sci202641898498PubTator, text miningPubMed
Improved method for the generation of double Holliday junction DNAs.Anal Biochem202641895433PubTator, text miningPubMed
MUS81 inhibits cell proliferation and migration in breast cancer by promoting the expression of CDKN2A(p16INK4a).Am J Transl Res202641868899PubTator, text miningPubMed
Dual-site phosphorylation of SLX4 stabilizes the SLX4-MUS81 interface to promote mitotic SMX assembly and genome protection.Nucleic Acids Res202641841343PubTator, text miningPubMed
EEPD1 evolved a unique DNA clamping dimer protecting reversed replication forks.Nucleic Acids Res202641830330PubTator, text miningPubMed
Cruciform-forming AT/TA repeats are acted upon by structure-selective endonucleases and Rad51 prior to repositioning to the nuclear periphery for repair.Nucleic Acids Res202641805125PubTator, text miningPubMed
Discovery of Two Structurally Distinct Classes of Inhibitors Targeting the Nuclease MUS81 and Enhancing Efficacy of Chemotherapy in Cancer Cells.J Med Chem202641740057PubTator, text miningPubMed
RAD51C-XRCC3 complex regulates FANCM-mediated R-loop resolution to safeguard genome integrity.Sci Adv202641719405PubTator, text miningPubMed
Cruciform-forming AT/TA repeats are acted upon by structure selective endonucleases and Rad51 prior to repositioning to the nuclear periphery for repair.bioRxiv202641648373PubTator, text miningPubMed
A system-level metastable model of cancer evolution: integrating replication stress, cell cycle deregulation and chromosomal instability.Ann Med202641606986PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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