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Gene · 8021

NUP214: nucleoporin 214

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NUP214: nucleoporin 214. Genes, record 8021. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8021

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Gene

Symbol
NUP214
HGNC
Name
nucleoporin 214
HGNC
NCBI Gene ID
8021
NCBI Gene
HGNC ID
HGNC:8064
HGNC
Ensembl
ENSG00000126883
NCBI Gene
Aliases
CAIN, CAN, D9S46E, IIAE9, N214
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P35658Nuclear pore complex protein Nup2142,0907Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1456327P35658Espacenet
EP 4641201 A22025-10-297703P35658Espacenet
JP 2025147176 A2025-10-069688P35658Espacenet
JP 2025529142 A2025-09-047203P35658Espacenet
US 12371689 B22025-07-297203P35658Espacenet
JP 2025517969 A2025-06-127703P35658Espacenet
JP 2025028160 A2025-02-289688P35658Espacenet
KR 1020250010750 A2025-01-219688P35658Espacenet
JP 2024109657 A2024-08-149695P35658Espacenet
JP 2022141755 A2022-09-29553P35658Espacenet

1 to 10 of 26

See all 26 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,200

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNUP214 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)352025
P30CA016672Cancer Center Support Grant142025
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement112025
U10CA180899Children's Oncology Group Statistics and Data Center112025
R01GM117360Molecular Basis of mRNA Export92025
R35CA197695Translating genomic discoveries to improved outcomes for high risk acute leukemia82025
P30CA008748Cancer Center Support Grant72025
P30CA016058Cancer Center Support Grant62025
P30CA030199Cancer Center Support Grant (CCSG)52025
R01CA080728Oncogenic Impact of eIF4E-dependent RNA Export in Cancer52025

1 to 10 of 1,200Source NIH's project files

See all 1,200 nih grants

Papers1,617

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Expandable DNA-origami rings as a nanomechanical platform for studying disordered nucleoporins.bioRxiv202642818085PubTator, text miningPubMed
Inhibition of nucleoporin 214 depletes leukemia stem cells by promoting heme catabolism and lipid peroxidation.Blood202642640860PubTator, text miningPubMed
Evolutionary study of oncogenes and tumor suppressor genes in breast carcinoma.J Taibah Univ Med Sci202642633313PubTator, text miningPubMed
Erythroblastic sarcoma with biallelic TP53 mutations and novel NUP214:: ABL1-new finding in erythroblastic sarcoma/acute erythroid leukemia.J Hematop202642611361PubTator, text miningPubMed
Adolescent onset of susceptibility to acute infection-induced encephalopathy-9 mimicking immune-mediated encephalitis.BMJ Case Rep202642575680PubTator, text miningPubMed
Beyond nuclear export: chromatin-bound XPO1/CRM1 as a transcriptional scaffold.Int J Hematol202642565971PubTator, text miningPubMed
The Geometry of Suspicion: Visual Exploration Patterns in Email Phishing Detection.J Eye Mov Res202642346320PubTator, text miningPubMed
Integrated clinicopathological, genomic, and immunophenotypic landscape of renal tubulocystic oncocytoma.Front Immunol202642058215PubTator, text miningPubMed
Deep Biological Clocks in Critical Care Medicine: A Scoping Review Toward Translational Precision Care.J Pers Med202641745384PubTator, text miningPubMed
Lamin B receptor upregulation in metastatic melanoma causes nuclear envelope fragility in confined migration during cancer invasion.Proc Natl Acad Sci U S A202641706894PubTator, text miningPubMed

1 to 10 of 1,617

See all 1,617 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8021

GET https://conductscience.org/api/genes/v1/8021/patents?page=2