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Gene · 8029

CUBN: cubilin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CUBN: cubilin. Genes, record 8029. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8029

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Gene

Symbol
CUBN
HGNC
Name
cubilin
HGNC
NCBI Gene ID
8029
NCBI Gene
HGNC ID
HGNC:2548
HGNC
Ensembl
ENSG00000107611
NCBI Gene
Aliases
IFCR, IGS, IGS1, MGA1, gp280
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60494Cubilin3,6232Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21319O60494Espacenet
JP 2026004568 A2026-01-1442528O60494Espacenet
EP 4650780 A22025-11-199972O60494Espacenet
EP 4640849 A22025-10-291509O60494Espacenet
EP 4641201 A22025-10-2910236O60494Espacenet
JP 2025147176 A2025-10-063772O60494Espacenet
JP 2025529142 A2025-09-046067O60494Espacenet
US 12371689 B22025-07-296067O60494Espacenet
JP 2025519096 A2025-06-241509O60494Espacenet
JP 2025517969 A2025-06-1210236O60494Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,130

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCUBN papersNewest fiscal year
P30CA016058Cancer Center Support Grant112025
P30DK063491Diabetes Research Center (DRC)62025
P01HL116263HDL Function in Human Disease42025
ZIACP010195Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study42025
P30CA062203Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025
P30CA076292Moffitt Cancer Center Support Grant32025
T32HL129982The Genetic Epidemiology of Heart, Lung, and Blood Traits Training Grant (GenHLB)32025
UL1TR001863Yale Clinical and Translational Science Award32025
UL1TR001881UCLA Clinical and Translational Science Institute32025

1 to 10 of 1,130Source NIH's project files

See all 1,130 nih grants

Papers1,462

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Spatial transcriptomic profiling of porcine tissue microarray detecting subclinical circovirus infection.Front Vet Sci202642824453PubTator, text miningPubMed
Diagnostic Overshadowing in Lennox-Gastaut Syndrome: Immerslund-Gräsbeck Syndrome Unmasked by Radiosurgical Stress.J Child Neurol202642669795PubTator, text miningPubMed
Case Report: Imerslund Grasbeck syndrome: a rare cause of megaloblastic anemia in a well-nourished child.Front Nutr202642661605PubTator, text miningPubMed
A Pilot Study of Urinary Cubilin Shedding in Type 1 Diabetes Mellitus: A Potential Biomarker to Predict Nephropathy.J Diabetes Res202642630017PubTator, text miningPubMed
COPI Coatomer Regulates Several Steps of HDL Metabolism.Arterioscler Thromb Vasc Biol202642592650PubTator, text miningPubMed
Genetic mutation patterns in Indonesian children with primary steroid-resistant nephrotic syndrome.Pediatr Nephrol202642420527PubTator, text miningPubMed
Immunometabolic Stratification of Autism Spectrum Disorder by CD4+ T-Cell Phenotype Reveals Subtype-Specific Energetic Deficit and Coordinated Suppression of Micronutrient Acquisition Pathways.Metabolites202642346396PubTator, text miningPubMed
Mapping metabolic reprogramming dynamics across pancreatic neuroendocrine tumor cell differentiation at single-cell transcriptomic resolution.Front Genet202642338981PubTator, text miningPubMed
Vitamin D as a cellular endocrine system: Tissue-specific microcircuits, immune reprogramming, and metabolic resistance.iScience202642291276PubTator, text miningPubMed
CUBN-AMN pathway loss in chronic benign proteinuria.Kidney Int202642233899PubTator, text miningPubMed

1 to 10 of 1,462

See all 1,462 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8029

GET https://conductscience.org/api/genes/v1/8029/patents?page=2