Gene · 8031
NCOA4: nuclear receptor coactivator 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NCOA4: nuclear receptor coactivator 4. Genes, record 8031. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8031
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13772 | Nuclear receptor coactivator 4 | 614 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents71
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 56105 | Q13772 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 56107 | Q13772 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 56112 | Q13772 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 17463 | Q13772 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15346 | Q13772 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 17463 | Q13772 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15346 | Q13772 | Espacenet |
| JP 2025024198 A | 2025-02-19 | 14131 | Q13772 | Espacenet |
| JP 2025024198 A | 2025-02-19 | 14132 | Q13772 | Espacenet |
| JP 2025024198 A | 2025-02-19 | 14133 | Q13772 | Espacenet |
1 to 10 of 71
See all 71 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,051
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NCOA4 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 36 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 17 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 10 | 2025 |
| R35GM131919 | The mechanism and regulation of autophagy | 8 | 2025 |
| T32CA009207 | Investigational Cancer Therapeutics Training Program (ICTTP) | 6 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 5 | 2025 |
| R01CA148828 | The role of HIF2alpha in colon carcinogenesis | 5 | 2025 |
| R01DK095201 | Control of iron absorption by intestinal HIF2 in iron and hematological disorders | 5 | 2025 |
| ZIADK054510 | Identification of human genes of iron homeostasis | 5 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 4 | 2025 |
1 to 10 of 1,051Source NIH's project files
See all 1,051 nih grantsPapers3,176
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Anesthesia inhalation agent sevoflurane induces perioperative cognitive impairment: Apelin/early growth response 1 axis induces ferritinophagy and exacerbates ferroptosis. | Med Gas Res | 2027 | 42734444 | PubTator, text mining | PubMed |
| From Genomic Insight to Clinical Impact: Dramatic Response in RET Fusion-positive Pancreatic Cancer. | Anticancer Res | 2026 | 42823154 | PubTator, text mining | PubMed |
| NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1-CH25H Axis. | Adv Sci (Weinh) | 2026 | 42811495 | PubTator, text mining | PubMed |
| The impact of RET fusions on radioiodine avidity and prognosis in patients with distant metastatic papillary thyroid cancer. | Endocrine | 2026 | 42804115 | PubTator, text mining | PubMed |
| Integrated Structural and Dynamic Analysis Reveals Destabilizing Effects of KRAS Missense Variants Associated with Lung Cancer. | Protein J | 2026 | 42791474 | PubTator, text mining | PubMed |
| Biophysical and molecular determinants of NCOA4-mediated ferritinophagy at the ferroptosis-inflammation interface: Compartmental iron transport, lipid oxidation, and causal constraints. | Prog Biophys Mol Biol | 2026 | 42759775 | PubTator, text mining | PubMed |
| Ferroptosis-neuroinflammation interplay: mechanistic pathways and therapeutic opportunities in central nervous system disorders. | Front Aging Neurosci | 2026 | 42755568 | PubTator, text mining | PubMed |
| MicroRNA-Ferroptosis-Spinal Cord Injury: A Complex Interplay in Neurodegeneration and Repair. | Int J Mol Sci | 2026 | 42737610 | PubTator, text mining | PubMed |
| Diagnostic and Predictive Values of Ferroptosis-Related Genes in Endometriosis Based on Integrated Bioinformatic Analysis. | Reprod Sci | 2026 | 42728524 | PubTator, text mining | PubMed |
| FTH1 mRNA-Protein Discordance in Cardiac Ferroptosis: Multilayer Posttranscriptional and Degradative Control. | Cardiovasc Ther | 2026 | 42723477 | PubTator, text mining | PubMed |
1 to 10 of 3,176
See all 3,176 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8031
GET https://conductscience.org/api/genes/v1/8031/patents?page=2