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PDCD1LG2: programmed cell death 1 ligand 2

1 protein, 322 patents, 1 drug, 0 trials, 4,008 NIH grants and 12,626 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPDCD1LG2HGNC
Nameprogrammed cell death 1 ligand 2HGNC
NCBI Gene ID80380NCBI Gene
HGNC IDHGNC:18731HGNC
EnsemblENSG00000197646NCBI Gene
AliasesB7-DC, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9BQ51Programmed cell death 1 ligand 22732Ensembl, GeneID, HGNCUniProt

Patents 322

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4831196 A22026-10-284Q9BQ51Espacenet
JP 2026120534 A2026-07-223Q9BQ51Espacenet
US 12637518 B22026-05-262Q9BQ51Espacenet
US 12624087 B22026-05-124Q9BQ51Espacenet
US 12612446 B22026-04-28446Q9BQ51Espacenet
JP 2026053733 A2026-03-25116Q9BQ51Espacenet
JP 2026035716 A2026-03-042Q9BQ51Espacenet
US 12559576 B22026-02-244Q9BQ51Espacenet
US 12503511 B22025-12-23116Q9BQ51Espacenet
JP 2025172069 A2025-11-20627Q9BQ51Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
RHIGM12B7CHEMBL2109309Programmed cell death 1 ligand 2 cross-linking agentCROSS-LINKING AGENTChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4008

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1452,025NIH's project files
P30CA016672Cancer Center Support Grant1002,025NIH's project files
P30CA006973Regional Oncology Research Center542,025NIH's project files
P50CA101942DF/HCC Kidney Cancer SPORE (supplement)332,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award322,025NIH's project files
P30CA016359Cancer Center Support Grant282,025NIH's project files
R01CA142779PD-1/PD-L1 modulation in cancer therapy272,025NIH's project files
P30CA047904Cancer Center Support Grant182,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant182,025NIH's project files
P30CA016058Cancer Center Support Grant162,025NIH's project files

Papers 12626

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821196PubTator, text miningPubMed
42799834PubTator, text miningPubMed
42796346PubTator, text miningPubMed
42780128PubTator, text miningPubMed
42777907PubTator, text miningPubMed
42777613PubTator, text miningPubMed
42776797PubTator, text miningPubMed
42765715PubTator, text miningPubMed
42754412PubTator, text miningPubMed
42741091PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license