Gene · 80854
SETD7: SET domain containing 7, histone lysine methyltransferase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SETD7: SET domain containing 7, histone lysine methyltransferase. Genes, record 80854. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/80854
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8WTS6 | Histone-lysine N-methyltransferase SETD7 | 366 | 32 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 63291 | Q8WTS6 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2885 | Q8WTS6 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2451 | Q8WTS6 | Espacenet |
| JP 2025118716 A | 2025-08-13 | 19 | Q8WTS6 | Espacenet |
| JP 2025118716 A | 2025-08-13 | 33 | Q8WTS6 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2451 | Q8WTS6 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2885 | Q8WTS6 | Espacenet |
| US 12285496 B2 | 2025-04-29 | 19 | Q8WTS6 | Espacenet |
| US 12285496 B2 | 2025-04-29 | 33 | Q8WTS6 | Espacenet |
| US 11807852 B2 | 2023-11-07 | 60 | Q8WTS6 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,025
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SETD7 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 15 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 6 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 6 | 2025 |
| P30CA023168 | Cancer Center Support Grant | 6 | 2025 |
| R01GM117275 | Protein N-terminal Methylation Mechanisms and Inhibition | 4 | 2025 |
| T32CA009302 | Leveraging innovative technologies in basic and clinical cancer research | 4 | 2025 |
| P01CA163227 | Androgen Receptor Action in Castration Resistant Prostate Cancer | 3 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 3 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 3 | 2025 |
1 to 10 of 1,025Source NIH's project files
See all 1,025 nih grantsPapers1,568
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The redox code of diabetic retinopathy: Decoding metabolic memory, predicting fate, and targeting heterogeneity. | Exp Eye Res | 2026 | 42601009 | PubTator, text mining | PubMed |
| Methyltransferase SETD7 as a Regulator of STING-Dependent Cytokine Response in Lung Cancer Cells. | Int J Mol Sci | 2026 | 42123601 | PubTator, text mining | PubMed |
| Single-cell insights into maladaptive endothelial plasticity and therapeutic targets in diabetic vascular complications. | Cardiovasc Diabetol | 2026 | 42092877 | PubTator, text mining | PubMed |
| The extracellular matrix: structure, composition, biological functions, diseases, and therapeutic targets. | Mol Biomed | 2026 | 41886037 | PubTator, text mining | PubMed |
| Cold exposure and human metabolism: A heterogeneous response across tissues and organs. | Temperature (Austin) | 2026 | 41797814 | PubTator, text mining | PubMed |
| Methyl-Lysine-Dependent Control of Protein Lifetime Through Lysine-Node Crosstalk and Reader-Coupled Degradation. | Biology (Basel) | 2026 | 41744639 | PubTator, text mining | PubMed |
| Histone H3K4 monomethyltransferase SETD7 promoted osteogenic differentiation of bone marrow mesenchymal stem cells exposed to Hydroquinone via autophagy. | Toxicol Lett | 2026 | 41740875 | PubTator, text mining | PubMed |
| Alterations in AR-FOXA1 signaling in prostate cancer progression and therapeutic resistance. | J Natl Cancer Cent | 2026 | 41738032 | PubTator, text mining | PubMed |
| Comprehensive analysis of the potential effect and mechanism of pyroptosis-related genes in treatment-related myeloid tumors. | PLoS One | 2026 | 41734196 | PubTator, text mining | PubMed |
| The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective. | Immun Inflamm Dis | 2026 | 41725222 | PubTator, text mining | PubMed |
1 to 10 of 1,568
See all 1,568 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/80854
GET https://conductscience.org/api/genes/v1/80854/patents?page=2