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Gene · 81030

ZBP1: Z-DNA binding protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ZBP1: Z-DNA binding protein 1. Genes, record 81030. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/81030

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Gene

Symbol
ZBP1
HGNC
Name
Z-DNA binding protein 1
HGNC
NCBI Gene ID
81030
NCBI Gene
HGNC ID
HGNC:16176
HGNC
Ensembl
ENSG00000124256
NCBI Gene
Aliases
C20orf183, DAI, DLM-1, DLM1, dJ718J7.3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H171Z-DNA-binding protein 14295Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1470098Q9H171Espacenet
WO 2025252547 A12025-12-11164Q9H171Espacenet
EP 4660322 A12025-12-10164Q9H171Espacenet
EP 4640849 A22025-10-291341Q9H171Espacenet
EP 4641201 A22025-10-299143Q9H171Espacenet
EP 4641202 A22025-10-295512Q9H171Espacenet
JP 2025147176 A2025-10-0615854Q9H171Espacenet
JP 2025519096 A2025-06-241341Q9H171Espacenet
JP 2025517969 A2025-06-129143Q9H171Espacenet
JP 2025028160 A2025-02-2815854Q9H171Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,562

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleZBP1 papersNewest fiscal year
R01AI124346Innate immune signaling and stress response382025
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation372025
R35CA253095Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancer262025
R01AI160179Targeting innate immune pathways, and inflammatory cell death in cytokine-mediated diseases202025
P01CA013106Targeting Transcription and Splicing in Cancer182025
P30CA006927Comprehensive Cancer Center Program at Fox Chase162025
R01AI135025Mechanism, Function, and Exploitation of Influenza A Virus-Activated Cell Death112025
R35CA231620MECHANISMS OF REGULATED CELL DEATH82025
R37AI044828Survival Function of the Fadd-Caspase-8-Flip Complex - MERIT Extension72025
R01NS083085Mechanism of mRNA Localization and Localized Translation in Neurons62025

1 to 10 of 1,562Source NIH's project files

See all 1,562 nih grants

Papers2,524

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Functional relevance and mechanisms of necroptosis in ischemia-reperfusion injury.Acta Neurobiol Exp (Wars)202642808676PubTator, text miningPubMed
FGF4 sustained-release nano-liposomes attenuate heat stroke-induced MODS by suppressing ZBP1-mediated programmed necrosis.Int Immunopharmacol202642805119PubTator, text miningPubMed
Tumour-associated dsRNA accumulation and innate immune activation: mechanistic basis and therapeutic strategies.EBioMedicine202642800308PubTator, text miningPubMed
Z-Nucleic Acid-Binding Protein (ZBP)1 (DAI/DLM1) Regulation in Antiviral Cell Death Pathways.Pathogens202642796741PubTator, text miningPubMed
Mitochondrial Quality Control Links Exercise to Sterile Inflammation in the Cardiovascular System: A Narrative Review.Antioxidants (Basel)202642792173PubTator, text miningPubMed
Mitochondria-associated programmed cell death in colorectal cancer: molecular mechanisms, metabolic plasticity, and therapeutic opportunities.Eur J Cell Biol202642790164PubTator, text miningPubMed
The Role of cGAS-STING-Driven PANoptosis in Neurodegenerative Diseases and Therapeutic Prospects.Cells202642782733PubTator, text miningPubMed
ZBP1 Evolution and Antagonism by Large DNA Viruses.J Mol Biol202642754087PubTator, text miningPubMed
Recent advances in PANoptosis research in kidney disease: mechanistic networks, pathological roles, and potential intervention strategies.Front Immunol202642713494PubTator, text miningPubMed
Emerging regulated cell death (cuproptosis, disulfidptosis, and PANoptosis) in ischemic stroke: research progress and translational prospects.Front Cell Dev Biol202642694396PubTator, text miningPubMed

1 to 10 of 2,524

See all 2,524 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/81030

GET https://conductscience.org/api/genes/v1/81030/patents?page=2