Gene · 8106
PABPN1: poly(A) binding protein nuclear 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PABPN1: poly(A) binding protein nuclear 1. Genes, record 8106. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8106
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q86U42 | Polyadenylate-binding protein 2 | 306 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 58350 | Q86U42 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 363 | Q86U42 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 363 | Q86U42 | Espacenet |
| WO 2024240908 A1 | 2024-11-28 | 41 | Q86U42 | Espacenet |
| US 11932852 B2 | 2024-03-19 | 74 | Q86U42 | Espacenet |
| JP 2023062092 A | 2023-05-02 | 74 | Q86U42 | Espacenet |
| KR 1020230020586 A | 2023-02-10 | 74 | Q86U42 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 64647 | Q86U42 | Espacenet |
| JP 2022540446 A | 2022-09-15 | 29070 | Q86U42 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 167618 | Q86U42 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants853
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PABPN1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| ZIAAG000511 | Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis | 6 | 2025 |
| R01AI123165 | Mechanisms of KSHV posttranscriptional gene regulation | 4 | 2025 |
| R35GM118136 | Regulation of mRNA processing: Mechanisms and Consequences | 4 | 2025 |
| ZIAAG000393 | Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging | 4 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 3 | 2025 |
| R35GM118080 | Structural studies of RNA processing and ubiquitin-like protein modification | 3 | 2025 |
| P01AI063302 | The intersection of innate and adaptive immunity to intracellular pathogens | 2 | 2025 |
| P20GM130457 | COBRE in Digestive and Liver Disease | 2 | 2025 |
| P30AG066509 | University of Washington Alzheimer's Disease Research Center | 2 | 2025 |
1 to 10 of 853Source NIH's project files
See all 853 nih grantsPapers1,471
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| PABPN1 pathogenic expansion in the UK Biobank: reframing genetic prevalence of oculopharyngeal muscular dystrophy. | J Neurol Neurosurg Psychiatry | 2026 | 42816172 | PubTator, text mining | PubMed |
| Rapid and reliable molecular diagnosis of oculopharyngeal muscular dystrophy: a cost-effective alternative for PABPN1 gene (GCN)n repeat analysis. | J Appl Genet | 2026 | 42809144 | PubTator, text mining | PubMed |
| [Preliminary exploration of BBOX1-AS1 as a potential biomarker involved in the regulation of tumor cell proliferation in non-small cell lung cancer]. | Zhonghua Zhong Liu Za Zhi | 2026 | 42764220 | PubTator, text mining | PubMed |
| Cancer-Associated Fibroblasts-Derived Exosomal METTL3 Drives Breast Cancer Malignancy by Eliciting PABPN1 m6A Modification. | Clin Breast Cancer | 2026 | 42721597 | PubTator, text mining | PubMed |
| Recent progress in emerging therapeutics and evaluation of oculopharyngeal muscular dystrophy. | Curr Opin Neurol | 2026 | 42630085 | PubTator, text mining | PubMed |
| Pathophysiological and translational implications of the dysregulation of molecular machineries controlling RNA metabolism in thyrotropinomas. | iScience | 2026 | 42602702 | PubTator, text mining | PubMed |
| A whole-transcriptome analysis of differentially expressed genes, transcripts, and transcript usage in blood samples from Parkinson's disease patients. | Exp Biol Med (Maywood) | 2026 | 42488690 | PubTator, text mining | PubMed |
| Beyond the Poly(A) Tail: The Expanding Functional Landscape of PABPN1 and Its Dysregulation in OPMD and Cancer. | Wiley Interdiscip Rev RNA | 2026 | 42469921 | PubTator, text mining | PubMed |
| Overexpression of Chimeric RNA by Retroviral Transduction. | Methods Mol Biol | 2026 | 42400794 | PubTator, text mining | PubMed |
| Frontotemporal lobar degeneration in a patient carrying a pathogenic PABPN1 expansion. | Neuroradiology | 2026 | 42387033 | PubTator, text mining | PubMed |
1 to 10 of 1,471
See all 1,471 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8106
GET https://conductscience.org/api/genes/v1/8106/patents?page=2