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Gene · 8106

PABPN1: poly(A) binding protein nuclear 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PABPN1: poly(A) binding protein nuclear 1. Genes, record 8106. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8106

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Gene

Symbol
PABPN1
HGNC
Name
poly(A) binding protein nuclear 1
HGNC
NCBI Gene ID
8106
NCBI Gene
HGNC ID
HGNC:8565
HGNC
Ensembl
ENSG00000100836
NCBI Gene
Aliases
OPMD, PAB2, PABII, PABP-2, PABP2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q86U42Polyadenylate-binding protein 23063Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1458350Q86U42Espacenet
EP 4650780 A22025-11-19363Q86U42Espacenet
JP 2025517970 A2025-06-12363Q86U42Espacenet
WO 2024240908 A12024-11-2841Q86U42Espacenet
US 11932852 B22024-03-1974Q86U42Espacenet
JP 2023062092 A2023-05-0274Q86U42Espacenet
KR 1020230020586 A2023-02-1074Q86U42Espacenet
US 11446398 B22022-09-2064647Q86U42Espacenet
JP 2022540446 A2022-09-1529070Q86U42Espacenet
JP 2022524081 A2022-04-27167618Q86U42Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants853

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePABPN1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant122025
ZIAAG000511Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis62025
R01AI123165Mechanisms of KSHV posttranscriptional gene regulation42025
R35GM118136Regulation of mRNA processing: Mechanisms and Consequences42025
ZIAAG000393Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging42025
P01CA092584Structural Cell Biology of DNA Repair Machines32025
R35GM118080Structural studies of RNA processing and ubiquitin-like protein modification32025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens22025
P20GM130457COBRE in Digestive and Liver Disease22025
P30AG066509University of Washington Alzheimer's Disease Research Center22025

1 to 10 of 853Source NIH's project files

See all 853 nih grants

Papers1,471

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
PABPN1 pathogenic expansion in the UK Biobank: reframing genetic prevalence of oculopharyngeal muscular dystrophy.J Neurol Neurosurg Psychiatry202642816172PubTator, text miningPubMed
Rapid and reliable molecular diagnosis of oculopharyngeal muscular dystrophy: a cost-effective alternative for PABPN1 gene (GCN)n repeat analysis.J Appl Genet202642809144PubTator, text miningPubMed
[Preliminary exploration of BBOX1-AS1 as a potential biomarker involved in the regulation of tumor cell proliferation in non-small cell lung cancer].Zhonghua Zhong Liu Za Zhi202642764220PubTator, text miningPubMed
Cancer-Associated Fibroblasts-Derived Exosomal METTL3 Drives Breast Cancer Malignancy by Eliciting PABPN1 m6A Modification.Clin Breast Cancer202642721597PubTator, text miningPubMed
Recent progress in emerging therapeutics and evaluation of oculopharyngeal muscular dystrophy.Curr Opin Neurol202642630085PubTator, text miningPubMed
Pathophysiological and translational implications of the dysregulation of molecular machineries controlling RNA metabolism in thyrotropinomas.iScience202642602702PubTator, text miningPubMed
A whole-transcriptome analysis of differentially expressed genes, transcripts, and transcript usage in blood samples from Parkinson's disease patients.Exp Biol Med (Maywood)202642488690PubTator, text miningPubMed
Beyond the Poly(A) Tail: The Expanding Functional Landscape of PABPN1 and Its Dysregulation in OPMD and Cancer.Wiley Interdiscip Rev RNA202642469921PubTator, text miningPubMed
Overexpression of Chimeric RNA by Retroviral Transduction.Methods Mol Biol202642400794PubTator, text miningPubMed
Frontotemporal lobar degeneration in a patient carrying a pathogenic PABPN1 expansion.Neuroradiology202642387033PubTator, text miningPubMed

1 to 10 of 1,471

See all 1,471 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8106

GET https://conductscience.org/api/genes/v1/8106/patents?page=2