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Gene · 8115

TCL1A: TCL1 family AKT coactivator A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TCL1A: TCL1 family AKT coactivator A. Genes, record 8115. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8115

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Gene

Symbol
TCL1A
HGNC
Name
TCL1 family AKT coactivator A
HGNC
NCBI Gene ID
8115
NCBI Gene
HGNC ID
HGNC:11648
HGNC
Ensembl
ENSG00000100721
NCBI Gene
Aliases
TCL1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P56279T-cell leukemia/lymphoma protein 1A1144Ensembl, GeneID, HGNC

Source UniProt

Patents70

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2024123008 A2024-09-108615P56279Espacenet
JP 2024123008 A2024-09-108616P56279Espacenet
JP 2024123008 A2024-09-108617P56279Espacenet
JP 2024123008 A2024-09-108618P56279Espacenet
JP 2022550377 A2022-12-0130P56279Espacenet
US 11446398 B22022-09-2087320P56279Espacenet
US 11446398 B22022-09-2087321P56279Espacenet
US 11446398 B22022-09-2087322P56279Espacenet
US 11446398 B22022-09-2087325P56279Espacenet
KR 1020220069032 A2022-05-2630P56279Espacenet

1 to 10 of 70

See all 70 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,240

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTCL1A papersNewest fiscal year
P30CA016672Cancer Center Support Grant352025
P30CA016058Cancer Center Support Grant232025
P30CA008748Cancer Center Support Grant142025
P50CA116201Mayo Clinic Breast Cancer SPORE112025
T32CA009056Tumor Cell Biology Training Program62025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant52025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202852025
R01CA177292Targeted Therapies for Lymphoid Malignancies52025
T32CA009120UCLA Tumor Immunology Institutional Training Grant52025
K12CA133250OSU K12 Training Grant in Oncology42025

1 to 10 of 1,240Source NIH's project files

See all 1,240 nih grants

Papers1,926

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Transcriptomic characterization of transitional B cells reveals four subsets with perturbed activation profiles in scleroderma.iScience202642774868PubTator, text miningPubMed
Multi-omics integration identifies prognostic genes linked to adaptive immunity response and radiosensitivity in cervical cancer.Transl Oncol202642767096PubTator, text miningPubMed
Case Report: Blastic plasmacytoid dendritic cell neoplasm mimicking systemic lymphoma: a multidisciplinary diagnostic challenge.Front Med (Lausanne)202642745818PubTator, text miningPubMed
Dual Loss of Surface CD3 and CD45 in a TCL1-Negative T-Prolymphocytic Leukemia With Concurrent CLL/SLL.Int J Lab Hematol202642665845PubTator, text miningPubMed
New insight into RNA biomarkers in neuropathic pain: a clinician-neuroscientist roadmap to translational testing and treatment monitoring a clinical review.Front Pain Res (Lausanne)202642534835PubTator, text miningPubMed
Targeting chitinase-3-like protein-1 in pancolitis by a drug-repurposing approach.Biochem Pharmacol202642508656PubTator, text miningPubMed
Taginostat, a new quinolone-based HDAC6 inhibitor, promotes apoptosis of chronic lymphocytic leukemia cells in vitro and in vivo by activating STAT4.Apoptosis202642400850PubTator, text miningPubMed
Integrative Analysis of Genetic Risk Factors for Acute Myeloid Leukemia Using Mendelian Randomization and Single-Cell RNA Sequencing Validation.Int J Genomics202642255490PubTator, text miningPubMed
The crotonylation reader DPF2 promotes the development and progression of colon adenocarcinoma through cell-type-specific immune regulation and metabolic reprogramming.Front Pharmacol202642232179PubTator, text miningPubMed
Mechanism of age-related accumulation of mtDNA mutations in human blood.Nature202642203880PubTator, text miningPubMed

1 to 10 of 1,926

See all 1,926 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8115

GET https://conductscience.org/api/genes/v1/8115/patents?page=2