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Gene · 814

CAMK4: calcium/calmodulin dependent protein kinase IV

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CAMK4: calcium/calmodulin dependent protein kinase IV. Genes, record 814. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/814

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Gene

Symbol
CAMK4
HGNC
Name
calcium/calmodulin dependent protein kinase IV
HGNC
NCBI Gene ID
814
NCBI Gene
HGNC ID
HGNC:1464
HGNC
Ensembl
ENSG00000152495
NCBI Gene
Aliases
CaMK IV, CaMK-GR, CaMKIV, caMK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16566Calcium/calmodulin-dependent protein kinase type IV4731Ensembl, GeneID, HGNC

Source UniProt

Patents62

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1439726Q16566Espacenet
JP 2026004568 A2026-01-1439728Q16566Espacenet
EP 4641201 A22025-10-292719Q16566Espacenet
JP 2025529142 A2025-09-04726Q16566Espacenet
US 12371689 B22025-07-29726Q16566Espacenet
JP 2025517969 A2025-06-122719Q16566Espacenet
JP 2025062604 A2025-04-1410937Q16566Espacenet
JP 2025062604 A2025-04-1410939Q16566Espacenet
JP 2025032204 A2025-03-1125710Q16566Espacenet
JP 2025032204 A2025-03-1125711Q16566Espacenet

1 to 10 of 62

See all 62 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,417

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCAMK4 papersNewest fiscal year
R01AI049954Gene Transcription in SLE122025
R01AI085567Expanded Double Negative T cells in SLE.62025
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged52025
P30CA016672Cancer Center Support Grant42025
P30CA062203Cancer Center Support Grant32025
T32MH079785Interdisciplinary And Translational Research Training In Neurohiv32025
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).32025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 522025
P20GM103427Nebraska Research Network in Functional Genomics22025
P20GM103434West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)22025

1 to 10 of 1,417Source NIH's project files

See all 1,417 nih grants

Papers1,734

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Multi-Ancestry Genome-wide Association Analyses Identify Shared and Specific Genetic Architecture in Mild and Moderate-to-Severe Asthma.medRxiv202642818167PubTator, text miningPubMed
GLP-1 Receptor Agonists as Molecular Relievers of Lipotoxic Stress: From Pancreatic Beta-Cell Cholesterol Efflux to Systemic and Tissue-Specific Metabolic Protection.Int J Mol Sci202642794805PubTator, text miningPubMed
ABCA1 as a Gatekeeper of Pancreatic β-Cell Cholesterol Homeostasis: Links Between Lipoprotein Stress, Lipotoxicity, and Insulin Secretion.Nutrients202642739051PubTator, text miningPubMed
Decreased H3K79 acetylation and dysregulation of neurodevelopmental genes in fetal down syndrome.Transl Pediatr202642724460PubTator, text miningPubMed
Multi-omics reveals the pituitary-mediated neuroendocrine mechanisms during the transition from the onset-of-birth to the laying period in Wanxi white geese.Poult Sci202642679723PubTator, text miningPubMed
Artemisinin Attenuates Aβ1-42 Aggregation via the CaMK IV/PKA-CREB-Ace-H4 Cascade in Neuronal Cultures and 3xTg-AD Models.Am J Chin Med202642623143PubTator, text miningPubMed
Correction to "Calhm6 Governs Macrophage Polarization Through Chp1-Camk4-Creb1 Axis and Ectosomal Delivery in Inflammatory Responses".Adv Sci (Weinh)202642474100PubTator, text miningPubMed
Osteocyte parvalbumin mediates mechanotransduction to attenuate osteoarthritis.Nat Commun202642448704PubTator, text miningPubMed
Solasodine, a Natural Steroidal Alkaloid, Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption: A Study Based on Network Pharmacology and Experimental Validation.J Cell Mol Med202642322165PubTator, text miningPubMed
Purinergic signaling promotes gliomagenesis through nuclear calcium transients.bioRxiv202642182450PubTator, text miningPubMed

1 to 10 of 1,734

See all 1,734 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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