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Gene · 8148

TAF15: TATA-box binding protein associated factor 15

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TAF15: TATA-box binding protein associated factor 15. Genes, record 8148. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8148

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Gene

Symbol
TAF15
HGNC
Name
TATA-box binding protein associated factor 15
HGNC
NCBI Gene ID
8148
NCBI Gene
HGNC ID
HGNC:11547
HGNC
Ensembl
ENSG00000270647
NCBI Gene
Aliases
Npl3, RBP56, TAF2N, TAFII68, hTAFII68
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92804TATA-binding protein-associated factor 2N59215Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026063308 A2026-03-2623Q92804Espacenet
JP 2026004568 A2026-01-1466357Q92804Espacenet
JP 2026004568 A2026-01-1466358Q92804Espacenet
EP 4650780 A22025-11-1918095Q92804Espacenet
JP 2025529142 A2025-09-044574Q92804Espacenet
US 12371689 B22025-07-294574Q92804Espacenet
JP 2025517970 A2025-06-1218095Q92804Espacenet
US 11446398 B22022-09-2086529Q92804Espacenet
US 11446398 B22022-09-2086536Q92804Espacenet
JP 2022524081 A2022-04-27189500Q92804Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,134

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTAF15 papersNewest fiscal year
P30CA008748Cancer Center Support Grant182025
P30CA021765Cancer Center Support Grant (CCSG)92025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions72025
P50CA217694SPORE in Soft Tissue Sarcoma52025
R01GM140127An Integrated Biochemical and Structural Approach to Delineating the Biology of EWSR152025
R35CA197695Translating genomic discoveries to improved outcomes for high risk acute leukemia52025
P30CA016672Cancer Center Support Grant42025
R35GM138186Quantifying Physiologic and Pathologic Viscoelastic Phases of Biomolecular Condensates by Correlative Force and Fluorescence Microscopy42025
P01CA155258Integrative Oncogenomics of Multiple Myeloma32025
P30AI027763UCSF-Bay Area Center for AIDS Research32025

1 to 10 of 1,134Source NIH's project files

See all 1,134 nih grants

Papers1,682

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Insertion or deletion variants in TAF15 exon 15 are genetic factors impacting the prognosis of amyotrophic lateral sclerosis in a Japanese cohort.Eur J Hum Genet202642823490PubTator, text miningPubMed
Conformational insights into the unfolding pathway of RNA recognition motif (RRM) domain of TAF15 associated with amyotrophic lateral sclerosis.J Biomol Struct Dyn202642802700PubTator, text miningPubMed
ALK overexpression without rearrangement widely exists in EWSR1/FUS-rearranged soft tissue tumours.J Clin Pathol202642660639PubTator, text miningPubMed
Elevated neuronal TAF15 expression induces oxidative stress and anxiety-related behavioral deficits.Cell Rep202642623241PubTator, text miningPubMed
Exploring Potential Stress Granule-Related Biomarkers in Childhood Asthma Using Integrated Bioinformatics and Machine Learning.J Inflamm Res202642592402PubTator, text miningPubMed
TAF15 amyloids propagate via defined motifs in a prion-like fashion.Nat Commun202642443203PubTator, text miningPubMed
CircTAF15 (hsa_circ_0043138) promotes NSCLC progression through stabilizing YBX1 to initiate GOT1 transcription.Int J Biol Macromol202642425339PubTator, text miningPubMed
FET proteins and PARylation-dependent condensates promote replication fork reversal and genome stability.Nat Commun202642380136PubTator, text miningPubMed
TAF15-mediated m5C modification of MTHFD2 RNA reveals a novel therapeutic target for IDH mutant gliomas.Biomark Res202642374521PubTator, text miningPubMed
UCMSC-derived exosomal circDLGAP4 enhances HFF-1 cell proliferation and migration by promoting ZNF217 promoter H3K27 acetylation.Mol Genet Genomics202642191952PubTator, text miningPubMed

1 to 10 of 1,682

See all 1,682 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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