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Gene · 815

CAMK2A: calcium/calmodulin dependent protein kinase II alpha

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CAMK2A: calcium/calmodulin dependent protein kinase II alpha. Genes, record 815. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/815

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Gene

Symbol
CAMK2A
HGNC
Name
calcium/calmodulin dependent protein kinase II alpha
HGNC
NCBI Gene ID
815
NCBI Gene
HGNC ID
HGNC:1460
HGNC
Ensembl
ENSG00000070808
NCBI Gene
Aliases
CAMKA, CaMKIINalpha, CaMKIIalpha, CaMKIIα, KIAA0968, MRD53, MRT63
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha47822Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1439689Q9UQM7Espacenet
JP 2025529142 A2025-09-04722Q9UQM7Espacenet
US 12371689 B22025-07-29722Q9UQM7Espacenet
JP 2025062604 A2025-04-1410893Q9UQM7Espacenet
JP 2025032204 A2025-03-1125696Q9UQM7Espacenet
EP 4461818 A22024-11-1325696Q9UQM7Espacenet
JP 2024510911 A2024-03-1243Q9UQM7Espacenet
KR 1020230152070 A2023-11-0239Q9UQM7Espacenet
JP 2023058610 A2023-04-2525696Q9UQM7Espacenet
US 11446398 B22022-09-2010893Q9UQM7Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,112

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCAMK2A papersNewest fiscal year
P30CA068485Cancer Center Support Grant52025
P30DK020593Vanderbilt Diabetes Research Center52025
P30EY008126Core Grant in Vision Research42025
R01AG013622Molecular, Cellular and Circuit Mechanisms for Age-Related Deficits in Memory-Linking42025
R01AG050986Higher Order Chromatin and Genetic Risk for Alzheimer's Disease42025
T32AG000222Training in the Molecular Biology of Neurodegeneration and Alzheimer's Disease42025
P01DA047233Transcriptional Mechanisms of Drug Addiction32025
P20GM103446Delaware INBRE32025
P30AG066507Johns Hopkins Alzheimer's Disease Research Center32025
P30AG072975Rush Alzheimer's Disease Research Center32025

1 to 10 of 2,112Source NIH's project files

See all 2,112 nih grants

Papers1,751

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[CAMK2a Regulates Paclitaxel Resistance in Oral Squamous Cell Carcinoma Cells by Activating the ERK Signaling Pathway].Sichuan Da Xue Xue Bao Yi Xue Ban202642688348PubTator, text miningPubMed
Prognostic model based on calcium-related genes predicts prognosis and reveals the immune landscape of acute myeloid leukemia.Exp Hematol202642641680PubTator, text miningPubMed
Brain-wide activity mapping reveals the somatosensory cortex as a sex-specific regulator of hedonic feeding.Neuropsychopharmacology202642618596PubTator, text miningPubMed
Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A-Dependent CXCL5 Upregulation.Adv Sci (Weinh)202642615356PubTator, text miningPubMed
Diagnostic Yield of Whole Exome Sequencing in Autism Spectrum Disorder Patients at a Tertiary Center in Saudi Arabia.J Autism Dev Disord202642606785PubTator, text miningPubMed
Spinal glycine receptor alpha 1 coordinates startle behavior through a cell-type specific mechanism.Int J Biol Sci202642524505PubTator, text miningPubMed
A novel glioma prognosis marker CAMK2A is related to immune microenvironment and may be involved in Ras/Raf/MEK/ERK signaling.Sci Rep202642350523PubTator, text miningPubMed
Sulfonadyn Compounds: A Class of Aryl Sulfonamides That Inhibit Dynamin GTPase and Clathrin-Mediated Endocytosis and Are Antiepileptic in Animal Models.ACS Chem Biol202642313002PubTator, text miningPubMed
CELF2-dependent RNA Regulation Supports Cortical Architecture and Synaptic Stability During Early Brain Development.Mol Neurobiol202642189331PubTator, text miningPubMed
Correction: miR-221 Exerts Antiviral and Anti-Inflammatory Effects against HSV-1 Through Direct Repression of CAMK2A and Immune Pathway Activation.Inflammation202642101674PubTator, text miningPubMed

1 to 10 of 1,751

See all 1,751 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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