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Gene · 816

CAMK2B: calcium/calmodulin dependent protein kinase II beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CAMK2B: calcium/calmodulin dependent protein kinase II beta. Genes, record 816. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/816

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Gene

Symbol
CAMK2B
HGNC
Name
calcium/calmodulin dependent protein kinase II beta
HGNC
NCBI Gene ID
816
NCBI Gene
HGNC ID
HGNC:1461
HGNC
Ensembl
ENSG00000058404
NCBI Gene
Aliases
CAM2, CAMK2, CAMKB, CaMKIIbeta, CaMKIIβ, MRD54
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta6664Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1439699Q13554Espacenet
EP 4640849 A22025-10-291761Q13554Espacenet
EP 4641201 A22025-10-2911785Q13554Espacenet
JP 2025529142 A2025-09-04723Q13554Espacenet
US 12371689 B22025-07-29723Q13554Espacenet
JP 2025523953 A2025-07-25169Q13554Espacenet
JP 2025519096 A2025-06-241761Q13554Espacenet
JP 2025517969 A2025-06-1211785Q13554Espacenet
JP 2025062604 A2025-04-1410905Q13554Espacenet
US 11892452 B22024-02-06137Q13554Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,436

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCAMK2B papersNewest fiscal year
P30CA016672Cancer Center Support Grant62025
P30CA015704Cancer Center Support Grant42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)32025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
P30GM124169ALS Efficiently Networking Advanced Beam Line Experiments (ALS-ENABLE)32025
U54NS123743Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets32025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes22025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 522025
P30AG066511Goizueta Alzheimer's Disease Research Center22025

1 to 10 of 1,436Source NIH's project files

See all 1,436 nih grants

Papers1,549

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
AI-powered histopathology classifiers identify transcriptomic biomarkers associated with cell cycle regulation and increased mitotic activity in poorly differentiated neuroendocrine carcinoma.Hum Genomics202642800881PubTator, text miningPubMed
CaMKIIβ Signaling drives expression of metabolic and stress response genes in skeletal muscle, and its loss contributes to the LGMDR1 phenotype.Hum Mol Genet202642725915PubTator, text miningPubMed
[CAMK2a Regulates Paclitaxel Resistance in Oral Squamous Cell Carcinoma Cells by Activating the ERK Signaling Pathway].Sichuan Da Xue Xue Bao Yi Xue Ban202642688348PubTator, text miningPubMed
Unc-51 like kinase 3 induces reticulophagy by mediating the GLI1/CAMK2B signaling pathway to promote the malignant progression of prostate cancer.Am J Cancer Res202642465026PubTator, text miningPubMed
Multi-Target Cardioprotective Potential of Garcinia indica Choisy in Olanzapine-Induced Cardiometabolic Dysregulation: Evidence From Computational and Experimental Insights in H9c2(2-1) Cells.Chem Biodivers202642460687PubTator, text miningPubMed
Exploration of new biomarkers for rheumatoid arthritis based on plasma proteomics and transcriptome integrated with genome-wide Mendelian randomization.J Autoimmun202642456406PubTator, text miningPubMed
CAMKV is an ISG and facilitates the degradation of rabies virus phosphoprotein via SQSTM1-mediated selective autophagy.Autophagy202642402699PubTator, text miningPubMed
CAMK2D isoform 15 facilitates gefitinib resistance via AKT phosphorylation in lung adenocarcinoma.Cancer Biol Med202642152470PubTator, text miningPubMed
A novel pharmacological inhibitor of MAP4K4 activity attenuates metabolic dysfunction-associated steatohepatitis.JHEP Rep202642092620PubTator, text miningPubMed
Construction of a risk scoring model based on machine learning and validation of the role of the key gene SERPINE1 in the progression of colon cancer.Cancer Cell Int202642087164PubTator, text miningPubMed

1 to 10 of 1,549

See all 1,549 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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