ConductScience.org, home

Gene · 81608

FIP1L1: factor interacting with PAPOLA and CPSF1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. FIP1L1: factor interacting with PAPOLA and CPSF1. Genes, record 81608. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/81608

On this page

Gene

Symbol
FIP1L1
HGNC
Name
factor interacting with PAPOLA and CPSF1
HGNC
NCBI Gene ID
81608
NCBI Gene
HGNC ID
HGNC:19124
HGNC
Ensembl
ENSG00000145216
NCBI Gene
Aliases
DKFZp586K0717, FIP1, Rhe, hFip1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6UN15Pre-mRNA 3'-end-processing factor FIP15943Ensembl, GeneID, HGNC

Source UniProt

Patents17

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446372Q6UN15Espacenet
EP 4650780 A22025-11-196216Q6UN15Espacenet
JP 2025517970 A2025-06-126216Q6UN15Espacenet
US 11446398 B22022-09-2029301Q6UN15Espacenet
JP 2022524081 A2022-04-27132272Q6UN15Espacenet
JP 2019054813 A2019-04-11226807Q6UN15Espacenet
JP 2017121241 A2017-07-13226807Q6UN15Espacenet
JP 2015516143 A2015-06-08226807Q6UN15Espacenet
US 8586006 B22013-11-1931561Q6UN15Espacenet
US 8168602 B22012-05-01770Q6UN15Espacenet

1 to 10 of 17

See all 17 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants885

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFIP1L1 papersNewest fiscal year
ZIAAI001130Eosinophils and Eosinophil Activation in the Pathogenesis of Human Disease312025
P30CA016672Cancer Center Support Grant232025
ZIAAI000249The Pathogenesis, Diagnosis, and Treatment of Systemic Mast Cell Disorders102025
R01DK064380Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and Ciliogenesis82025
ZIACL080004Laboratory Assessment of Patients with Hypereosinophilic Syndrome82025
P30CA008748Cancer Center Support Grant62025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias52025
P30CA047904Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant52025
R01DK048370Small GTP Binding Proteins in Gastrointestinal Mucosa52025

1 to 10 of 885Source NIH's project files

See all 885 nih grants

Papers2,072

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Molecular Mechanism of Reduced RhCE Antigen and Precision Transfusion].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642802453PubTator, text miningPubMed
A functional view on the enhanced therapeutic effects of the control-released recombinant human endostatin.Am J Nucl Med Mol Imaging202642787631PubTator, text miningPubMed
Complete Remission to Imatinib in a Myeloid Neoplasm with Basophilia and PRKG2::PDGFRA Gene Fusion: A Case Report.Acta Haematol202642700436PubTator, text miningPubMed
Hypereosinophilic syndrome and suspected myeloid neoplasia in relapsed Hodgkin lymphoma during immune checkpoint inhibitor therapy: a rare case.Leuk Lymphoma202642669182PubTator, text miningPubMed
Acute myeloid leukemia with 4q12 rearrangements involving CHIC2: "pitfalls" in fluorescence in situ hybridization diagnosis of PDGFRA rearrangements.Am J Clin Pathol202642556331PubTator, text miningPubMed
Organ Involvement and Constitutional Symptoms in Idiopathic Hypereosinophilic Syndrome: A 72-Patient Single-Centre Cohort.J Clin Med202642513483PubTator, text miningPubMed
Severe persistent hypereosinophilia of undetermined significance: diagnostic challenges in clinical practice and two-year follow-up.Rom J Intern Med202642335361PubTator, text miningPubMed
Loeffler Endocarditis: Multimodality Imaging of a Common Cardiac Phenotype in Distinct Hypereosinophilic Syndromes.JACC Case Rep202642301176PubTator, text miningPubMed
Bilateral temporal arteritis with multiorgan eosinophilic infiltration treated with IL-5 targeted antibody.Rheumatol Int202642207305PubTator, text miningPubMed
Hypereosinophilic endocarditis presenting with intracardiac mass and severe mitral regurgitation: a case report of FIP1L1-PDGFRA positive myeloid neoplasm.Eur Heart J Case Rep202642130655PubTator, text miningPubMed

1 to 10 of 2,072

See all 2,072 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/81608

GET https://conductscience.org/api/genes/v1/81608/patents