Gene · 8165
AKAP1: A-kinase anchoring protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. AKAP1: A-kinase anchoring protein 1. Genes, record 8165. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8165
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q92667 | A-kinase anchor protein 1, mitochondrial | 903 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents43
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 35869 | Q92667 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 35871 | Q92667 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6305 | Q92667 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 356 | Q92667 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 356 | Q92667 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6305 | Q92667 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 585 | Q92667 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 587 | Q92667 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 594 | Q92667 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 595 | Q92667 | Espacenet |
1 to 10 of 43
See all 43 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,333
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | AKAP1 papers | Newest fiscal year |
|---|---|---|---|
| R01DK073368 | Mechanisms of Compartmentalized cAMP Signaling | 17 | 2025 |
| R01DK119192 | Defective PKA Signaling in Cushing's Syndrome | 10 | 2025 |
| R35CA197622 | Live-cell Activity Architecture in Cancer | 9 | 2025 |
| T32CA009523 | Contemporary Approaches to Cancer Cell Signaling and Communication | 7 | 2025 |
| T32DK007247 | Diabetes, Obesity and Metabolism Training Program | 4 | 2025 |
| P20GM130459 | Nevada Center of Biomedical Research Excellence in Molecular and Cellular Signal Transduction in the Cardiovascular System | 3 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 3 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 3 | 2025 |
| R01DK080834 | Inhibition of an Apical cAMP/cGMP Transporter (MRP4) in the Gut Induces Diarrhea | 3 | 2025 |
| R01HL058506 | G Protein-Coupled Receptor Regulation in Airway Myocytes | 3 | 2025 |
1 to 10 of 1,333Source NIH's project files
See all 1,333 nih grantsPapers1,448
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
Corrigendum to "AKAP1 orchestrates mitochondrial dynamics and metabolic reprogramming to promote hypoxia tolerance in yak cardiac fibroblasts" [International Journal of Biological Macromolecules, Volume 380 (2026) 154073]. | Int J Biol Macromol | 2026 | 42772968 | PubTator, text mining | PubMed |
| High-yield on-resin synthesis of doubly crosslinked α-helical peptides with significantly improved protease resistance using an isophthalic acid-based crosslinker. | Eur J Med Chem | 2026 | 42772125 | PubTator, text mining | PubMed |
| A-kinase anchoring protein complexes and cAMP signaling within the dorsal root ganglia in chronic pain. | Mol Pharmacol | 2026 | 42664595 | PubTator, text mining | PubMed |
| [Retracted] Epigenetic silencing of microRNA-199a-5p promotes the proliferation of non-small cell lung cancer cells by increasing AKAP1 expression. | Oncol Lett | 2026 | 42577711 | PubTator, text mining | PubMed |
| Norepinephrine attenuates acute lung injury by protecting mitochondria via the β2-AR-AKAP1 axis and inhibiting alveolar epithelial pyroptosis. | Redox Biol | 2026 | 42378955 | PubTator, text mining | PubMed |
| AKAP signaling: physiological and pathophysiological roles and opportunities for novel therapeutic concepts. | Physiol Rev | 2026 | 42155599 | PubTator, text mining | PubMed |
| Deciphering Bax Dynamics: Regulation, Retrotranslocation, and Mitochondrial Interplay in the Commitment to Apoptosis: A Narrative Review. | Health Sci Rep | 2026 | 42124878 | PubTator, text mining | PubMed |
| Biophysical and aerodynamic properties of a peptide targeting the A-kinase anchoring function of PI3Kγ for pulmonary cAMP modulation. | Sci Rep | 2026 | 42009784 | PubTator, text mining | PubMed |
| The Role of A-Kinase Anchoring Proteins for Inhibitory cAMP Signalling in Platelets. | Cells | 2026 | 41892342 | PubTator, text mining | PubMed |
| MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway. | Cell Death Discov | 2026 | 41876468 | PubTator, text mining | PubMed |
1 to 10 of 1,448
See all 1,448 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8165
GET https://conductscience.org/api/genes/v1/8165/patents?page=2