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Gene · 8233

ZRSR2: zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ZRSR2: zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. Genes, record 8233. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8233

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Gene

Symbol
ZRSR2
HGNC
Name
zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
HGNC
NCBI Gene ID
8233
NCBI Gene
HGNC ID
HGNC:23019
HGNC
Ensembl
ENSG00000169249
NCBI Gene
Aliases
OFD21, U2AF1-RS2, U2AF1L2, U2AF1RS2, URP, ZC3H22
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15696U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 24820Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1470128Q15696Espacenet
EP 4650780 A22025-11-194183Q15696Espacenet
JP 2025517970 A2025-06-124183Q15696Espacenet
JP 2024507735 A2024-02-21149Q15696Espacenet
US 11446398 B22022-09-2098471Q15696Espacenet
JP 2022524081 A2022-04-27201442Q15696Espacenet
JP 2022512773 A2022-02-0729Q15696Espacenet
US 11078247 B22021-08-0313043Q15696Espacenet
EP 3813826 A12021-05-0528Q15696Espacenet
WO 2020089892 A12020-05-0727Q15696Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants694

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleZRSR2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant332025
P30CA016672Cancer Center Support Grant172025
R01HL128239Genetic and molecular basis for SRSF2 mutations in myelodysplasia172025
U10CA180821Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension152025
U10CA180882Alliance Statistics and Data Management Center152025
U24CA196171The Alliance NCTN Biorepository and Biospecimen Resource152025
P30CA016058Cancer Center Support Grant142025
R01GM070503Molecular Recognition During Pre-mRNA Splicing82025
UG1CA233338ITSC for Leukemia: Novel Molecular strategies for NCTN "Individualized" Therapies82025
P30CA076292Moffitt Cancer Center Support Grant72025

1 to 10 of 694Source NIH's project files

See all 694 nih grants

Papers1,303

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genomic and clinical determinants of response to Azacitidine plus venetoclax in acute myeloid leukemia: Results from the HM-SCREEN-Japan 02 study.PLoS One202642821569PubTator, text miningPubMed
Serial VAF Kinetics Reveal Dynamic Clonal Evolution Associated With Progression in Clonal Cytopenia of Undetermined Significance.Eur J Haematol202642728663PubTator, text miningPubMed
Targeting splicing-derived neoantigens for precision cancer immunotherapy.Front Immunol202642724627PubTator, text miningPubMed
Splicing modulation as an emerging therapeutic strategy in cancer: molecular mechanisms, clinical development, and future perspectives.Jpn J Clin Oncol202642704825PubTator, text miningPubMed
Low-grade osteogenic tumor with secondary aneurysmal bone cyst: Distinguishing osteoblastoma from low-grade osteosarcoma in the setting of noncanonical molecular findings.Radiol Case Rep202642668586PubTator, text miningPubMed
Distinct clinical and genetic characteristics of myelodysplastic syndrome in younger patients.Br J Haematol202642630001PubTator, text miningPubMed
Pervasive noise in human pre-mRNA splice site selection.Mol Cell202642607686PubTator, text miningPubMed
Acute Myeloid Leukemia with Myelodysplasia-Related Gene Mutations.J Clin Med202642590061PubTator, text miningPubMed
Additional myelodysplasia-related gene mutations alter clinical presentation and worsen prognosis in patients with SRSF/TET2 co-mutated myeloid neoplasms.Leuk Lymphoma202642584663PubTator, text miningPubMed
The histopathological differential diagnosis of BPDCN and other plasmacytoid dendritic cell proliferations.Virchows Arch202642563016PubTator, text miningPubMed

1 to 10 of 1,303

See all 1,303 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8233

GET https://conductscience.org/api/genes/v1/8233/patents?page=2