Gene · 8239
USP9X: ubiquitin specific peptidase 9 X-linked
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. USP9X: ubiquitin specific peptidase 9 X-linked. Genes, record 8239. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8239
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q93008 | Ubiquitin carboxyl-terminal hydrolase 9X | 2,554 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents14
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69028 | Q93008 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10029 | Q93008 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10309 | Q93008 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10309 | Q93008 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10029 | Q93008 | Espacenet |
| JP 2023551068 A | 2023-12-06 | 238 | Q93008 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 95059 | Q93008 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 198030 | Q93008 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 249463 | Q93008 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 249463 | Q93008 | Espacenet |
1 to 10 of 14
See all 14 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,243
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | USP9X papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 7 | 2025 |
| P20GM103430 | Rhode Island IDeA Network of Biomedical Research Excellence | 6 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| R01EY026635 | Protein-polymer nanomedicine for Sjogren's Syndrome | 5 | 2025 |
| R01MH107182 | Postsynaptic roles of ankyrins | 5 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 4 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,243Source NIH's project files
See all 1,243 nih grantsPapers1,917
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Transketolase-like 1 potentiates PD-1 blockade in hepatocellular carcinoma by glycolysis to prime dendritic cell lactylation. | Signal Transduct Target Ther | 2026 | 42802226 | PubTator, text mining | PubMed |
| Interactions Between E3 Ubiquitin Ligases and Deubiquitinases in AKT Regulation: Implications in Skeletal Muscle Homeostasis. | Cell Biochem Funct | 2026 | 42671015 | PubTator, text mining | PubMed |
| Atractylenolide I alleviates LPS-induced pulmonary cell injury relevant to pediatric pneumonia via the ERK/USP9X/Mcl-1 and Akt/Survivin axes. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42624927 | PubTator, text mining | PubMed |
| Palmitoylation of TK1 exacerbates osteoarthritis by promoting JNK-mediated metabolic reprogramming. | Proc Natl Acad Sci U S A | 2026 | 42546205 | PubTator, text mining | PubMed |
| Insufficiency of cohesin regulatory protein PDS5B triggers meiotic failure and aneuploidy in oocytes during advanced maternal aging. | Proc Natl Acad Sci U S A | 2026 | 42531021 | PubTator, text mining | PubMed |
| The Deubiquitinating Enzyme USP9X Regulates the Protein Stability of the FAM49B in Clear Cell Renal Cell Carcinoma. | J Proteome Res | 2026 | 42463156 | PubTator, text mining | PubMed |
| Bioinformatics screening identifies USP9X as a pathogenic gene underlying thyroid and breast cancer comorbidity. | J Mol Histol | 2026 | 42417888 | PubTator, text mining | PubMed |
| USP9X trims STAT1 to curb oncostatin M activity and intestinal inflammation. | Cell Mol Immunol | 2026 | 42350601 | PubTator, text mining | PubMed |
| HSPA6 Confers Lenvatinib Resistance in Hepatocellular Carcinoma by Promoting Phase Separation-Mediated TXNRD1 Stabilization to Suppress Ferroptosis. | Cancer Res | 2026 | 42314062 | PubTator, text mining | PubMed |
| Recurrent COPA mutation drives R-spondin-independent Wnt activation in intestinal tumors. | Nat Genet | 2026 | 42286202 | PubTator, text mining | PubMed |
1 to 10 of 1,917
See all 1,917 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8239
GET https://conductscience.org/api/genes/v1/8239/patents