Gene · 825
CAPN3: calpain 3
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. CAPN3: calpain 3. Genes, record 825. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/825
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P20807 | Calpain-3 | 821 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents64
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026094287 A | 2026-06-09 | 7 | P20807 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 39798 | P20807 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 12001 | P20807 | Espacenet |
| JP 2025523953 A | 2025-07-25 | 151 | P20807 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 12001 | P20807 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 11161 | P20807 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 25765 | P20807 | Espacenet |
| EP 4505469 A2 | 2025-02-12 | 989 | P20807 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 25765 | P20807 | Espacenet |
| JP 2024533973 A | 2024-09-18 | 47 | P20807 | Espacenet |
1 to 10 of 64
See all 64 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants794
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CAPN3 papers | Newest fiscal year |
|---|---|---|---|
| ZIANS003129 | Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 3 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 3 | 2025 |
| P50NS053672 | Muscular Dystrophy Specialized Research Center | 3 | 2025 |
| R01EY024698 | Gene Editing and Silencing in Phototransduction | 3 | 2025 |
| ZIAAR041203 | Muscle Disease Unit | 3 | 2025 |
| K24AR073317 | Clinical and Translational studies in muscle disease | 2 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 794Source NIH's project files
See all 794 nih grantsPapers1,501
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Population Reference Data in the Molecular Diagnosis of Pathogenic CAPN3 Variants: Contextual Evidence and Interpretive Limits. | Mol Diagn Ther | 2026 | 42782423 | PubTator, text mining | PubMed |
| CaMKIIβ Signaling drives expression of metabolic and stress response genes in skeletal muscle, and its loss contributes to the LGMDR1 phenotype. | Hum Mol Genet | 2026 | 42725915 | PubTator, text mining | PubMed |
| Reply to: "Autosomal-Dominant Dystonia Associated with CAPN3 Variant". | Mov Disord | 2026 | 42716911 | PubTator, text mining | PubMed |
| Autosomal-Dominant Dystonia Associated with CAPN3 Variant. | Mov Disord | 2026 | 42713740 | PubTator, text mining | PubMed |
| Impaired Myogenic Differentiation Is a Shared Feature Across Genetic Myopathies. | Int J Mol Sci | 2026 | 42511681 | PubTator, text mining | PubMed |
| Withdrawal: Human calpain-3 and its structural plasticity: Dissociation of a homohexamer into dimers on binding titin. | J Biol Chem | 2026 | 42508284 | PubTator, text mining | PubMed |
| Defining Haplosufficiency in Autosomal Recessive Limb-Girdle Muscular Dystrophy Using Molecular Markers in Disease Carriers. | Neurol Genet | 2026 | 42453854 | PubTator, text mining | PubMed |
| Correction of aberrant splicing caused by intronic CAPN3 pathogenic variants using RNA-targeted therapeutic strategies in limb-girdle muscular dystrophy type R1. | Orphanet J Rare Dis | 2026 | 42288923 | PubTator, text mining | PubMed |
| Myoclonus-Dystonia Associated with Heterozygous CAPN3 Splice-Site Variant. | Mov Disord | 2026 | 42237535 | PubTator, text mining | PubMed |
| Expanding the Utility of Exome Sequencing in Preventive and Population Genetics. | Am J Med Genet A | 2026 | 42212615 | PubTator, text mining | PubMed |
1 to 10 of 1,501
See all 1,501 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/825
GET https://conductscience.org/api/genes/v1/825/patents?page=2