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Gene · 8288

EPX: eosinophil peroxidase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EPX: eosinophil peroxidase. Genes, record 8288. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8288

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Gene

Symbol
EPX
HGNC
Name
eosinophil peroxidase
HGNC
NCBI Gene ID
8288
NCBI Gene
HGNC ID
HGNC:3423
HGNC
Ensembl
ENSG00000121053
NCBI Gene
Aliases
EPO, EPP, EPX-PEN, EPXD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P11678Eosinophil peroxidase7151Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445067P11678Espacenet
EP 4650780 A22025-11-19624P11678Espacenet
EP 4641201 A22025-10-29438P11678Espacenet
JP 2025147176 A2025-10-064849P11678Espacenet
JP 2025529142 A2025-09-046284P11678Espacenet
US 12371689 B22025-07-296284P11678Espacenet
JP 2025517969 A2025-06-12438P11678Espacenet
JP 2025517970 A2025-06-12624P11678Espacenet
JP 2025028160 A2025-02-284849P11678Espacenet
KR 1020250010750 A2025-01-214849P11678Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,288

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEPX papersNewest fiscal year
ZIAAI001130Eosinophils and Eosinophil Activation in the Pathogenesis of Human Disease212025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease112025
U19AI070235Epithelial Genes in Allergic Inflammation112025
R01AI145108The Role of Donor-Derived Eosinophils on Lung Allograft Ischemia Reperfusion Injury52025
R01HL080414Phenotypic and biological features of mucus plugs in asthma52025
U2CTR002818Data Management and Coordinating Center: Rare Diseases Clinical Research Network52025
R01AI124355Genetic and Immunological Dissection of Eosinophilic Esophagitis42025
R01DK114457TWEAK/TNFSF12 and LIGHT/TNFSF14 interactions in allergic esophagitis remodeling42025
T32DK067009Institutional Training Grant in Pediatric Gastroenterology42025
ZIACL080004Laboratory Assessment of Patients with Hypereosinophilic Syndrome42025

1 to 10 of 1,288Source NIH's project files

See all 1,288 nih grants

Papers2,629

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Emerging roles of structural elements guiding human heme peroxidase function and interactions.Biochim Biophys Acta Proteins Proteom202642759823PubTator, text miningPubMed
Blood Eosinophil Subtype-Specific Protein Gene Expression and Eosinophil-Derived Serum Mediators in Allergic Asthma Patients After Bronchial Challenge with Dermatophagoides pteronyssinus.Cells202642738872PubTator, text miningPubMed
Interface N-glycans drive myeloperoxidase dimerization in vitro.Int J Biol Macromol202642735772PubTator, text miningPubMed
Mepolizumab Modifies Blood Eosinophil Proteome and Transcriptome in Severe Eosinophilic Asthma.Allergy202642655930PubTator, text miningPubMed
Eosinophil-associated intestinal immune responses following SARS-CoV-2 infection in K18-hACE2 mice.PLoS One202642585251PubTator, text miningPubMed
Eosinophil Essentials: Identification and Assessment of Activity.J Leukoc Biol202642372110PubTator, text miningPubMed
The Role of and Therapeutic Strategies for Eosinophils in Atopic Dermatitis.Biomedicines202642351638PubTator, text miningPubMed
Cytokine patterns in very low birth weight infants under different cord clamping strategies: preliminary EXPLAIN trial data.BMC Pediatr202642260466PubTator, text miningPubMed
Three-dimensional modeling of sensory nerve architecture and eosinophil and mast cell interactions in eosinophilic gastrointestinal disease.J Leukoc Biol202642118094PubTator, text miningPubMed
Autoallergy in chronic rhinosinusitis and its clinical relevance.World Allergy Organ J202642021980PubTator, text miningPubMed

1 to 10 of 2,629

See all 2,629 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8288

GET https://conductscience.org/api/genes/v1/8288/patents?page=2