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Gene · 8295

TRRAP: transformation/transcription domain associated protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TRRAP: transformation/transcription domain associated protein. Genes, record 8295. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8295

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Gene

Symbol
TRRAP
HGNC
Name
transformation/transcription domain associated protein
HGNC
NCBI Gene ID
8295
NCBI Gene
HGNC ID
HGNC:12347
HGNC
Ensembl
ENSG00000196367
NCBI Gene
Aliases
DEDDFA, DFNA75, PAF350/400, PAF400, STAF40, TR-AP, Tra1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y4A5Transformation/transcription domain-associated protein3,8599Ensembl, GeneID, HGNC

Source UniProt

Patents37

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12558356 B22026-02-2410Q9Y4A5Espacenet
JP 2026004568 A2026-01-1467499Q9Y4A5Espacenet
EP 4650780 A22025-11-197718Q9Y4A5Espacenet
EP 4641201 A22025-10-297765Q9Y4A5Espacenet
JP 2025529142 A2025-09-045082Q9Y4A5Espacenet
US 12371689 B22025-07-295082Q9Y4A5Espacenet
JP 2025517969 A2025-06-127765Q9Y4A5Espacenet
JP 2025517970 A2025-06-127718Q9Y4A5Espacenet
JP 2025024198 A2025-02-1916513Q9Y4A5Espacenet
US 11976334 B22024-05-07211Q9Y4A5Espacenet

1 to 10 of 37

See all 37 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,357

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTRRAP papersNewest fiscal year
P30CA016672Cancer Center Support Grant192025
P01CA092584Structural Cell Biology of DNA Repair Machines132025
ZIABC008752Thyroid Hormone Nuclear Receptors in Health and Disease92025
P30CA006973Regional Oncology Research Center62025
P30CA008748Cancer Center Support Grant62025
P30CA023108Cancer Center Support Grant52025
ZIABC011191Preclinical Mouse Models of Thyroid Cancer52025
P30CA015704Cancer Center Support Grant42025
P30CA056036Translational Research in Cancer42025
P30CA076292Moffitt Cancer Center Support Grant42025

1 to 10 of 1,357Source NIH's project files

See all 1,357 nih grants

Papers1,639

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Acetylation promotes thyroid hormone receptor ubiquitination and degradation by nuclear proteasomes.Mol Cell Endocrinol202742778016PubTator, text miningPubMed
TRRAP enables MMB-dependent mitotic transcription and determines sensitivity to CHK1 inhibition.Cell Rep202642731029PubTator, text miningPubMed
Serum Peptidomic Analysis in a Comparative Study of the Efficacy of Benjakul Remedy Versus Loratadine in Allergic Rhinitis Patients.Int J Mol Sci202642653391PubTator, text miningPubMed
Efficacy of synthetic ACTH in confirmed and presumed monogenic developmental and epileptic encephalopathies.Epileptic Disord202642615235PubTator, text miningPubMed
The Molecular Landscape of CASTLE: A Rare Thymus-like Head and Neck Cancer.Int J Mol Sci202642074143PubTator, text miningPubMed
Long-Term Follow Up of Two Patients With Variants in the Cluster 1031-1159 of TRRAP Gene: Expanding the Phenotype of Developmental Delay With or Without Dysmorphic Facies and Autism.Am J Med Genet A202641952423PubTator, text miningPubMed
Nucleolus as a cornerstone linking proliferation and metabolism to cellular responses to stress: involvement of transcription factors MYC and p53.Front Mol Biosci202641777667PubTator, text miningPubMed
CCorGsDB: a database for clock correlated genes in the mouse and human central nervous systems.NPJ Biol Timing Sleep202641775996PubTator, text miningPubMed
Reciprocal targeting of the unfolded protein response regulator Xbp1 and the DOM-A nucleosome remodeler in Drosophila.Nucleic Acids Res202641773014PubTator, text miningPubMed
Construction of circadian clock signature for tumor microenvironment in predicting survival of esophageal squamous cell carcinoma.Front Immunol202641766897PubTator, text miningPubMed

1 to 10 of 1,639

See all 1,639 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8295

GET https://conductscience.org/api/genes/v1/8295/patents?page=2