Gene · 8301
PICALM: phosphatidylinositol binding clathrin assembly protein
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PICALM: phosphatidylinositol binding clathrin assembly protein. Genes, record 8301. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8301
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13492 | Phosphatidylinositol-binding clathrin assembly protein | 652 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 57588 | Q13492 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 57589 | Q13492 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11015 | Q13492 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 11015 | Q13492 | Espacenet |
| JP 2025062601 A | 2025-04-14 | 24 | Q13492 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 62542 | Q13492 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 165513 | Q13492 | Espacenet |
| JP 2022523514 A | 2022-04-25 | 24 | Q13492 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 238023 | Q13492 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 238024 | Q13492 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,276
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PICALM papers | Newest fiscal year |
|---|---|---|---|
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 112 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 26 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 20 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 16 | 2025 |
| U24AG041689 | THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE | 16 | 2025 |
| U24AG056270 | National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS) | 14 | 2025 |
| U19AG024904 | Alzheimer's Disease Neuroimaging Initiative (ADNI4) | 12 | 2025 |
| P30AG072975 | Rush Alzheimer's Disease Research Center | 10 | 2025 |
| U54AG052427 | Genome Center for Alzheimer's Disease (GCAD) | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
1 to 10 of 2,276Source NIH's project files
See all 2,276 nih grantsPapers2,227
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Molecular and genetic basis of alzheimer's disease and emerging treatment Modalities. | Neurodegener Dis Manag | 2026 | 42825454 | PubTator, text mining | PubMed |
| Integrated plasma proteomic and metabolomic profiling demonstrated specific proteins and bile acids remodeling after liver transplantation of children with biliary atresia. | Biochim Biophys Acta Proteins Proteom | 2026 | 42777789 | PubTator, text mining | PubMed |
| Population Attributable Risk in Alzheimer and Parkinson Diseases. | Neurol Genet | 2026 | 42639394 | PubTator, text mining | PubMed |
| Tau dysfunction in alzheimer's disease: molecular and cellular mechanisms, genetic modulation, and therapeutic perspectives. | Mol Biol Rep | 2026 | 42593621 | PubTator, text mining | PubMed |
| Assessment of paralogue annotation for improving diagnostic accuracy in CALM1, CALM2, and CALM3 genes. | Front Genet | 2026 | 42524612 | PubTator, text mining | PubMed |
| Subtle cortical thinning in the temporal pole in middle-aged APOE-ε4 and PICALM (rs3851179) AA/AG carriers without dementia. | Neurobiol Aging | 2026 | 42508146 | PubTator, text mining | PubMed |
| Disease-predominant loci across Alzheimer's disease, Parkinson's disease and Lewy body dementia: evidence from the UK Biobank prospective cohort, conditional GWAS and colocalization. | Front Genet | 2026 | 42460153 | PubTator, text mining | PubMed |
| Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort. | PLoS Genet | 2026 | 42371968 | PubTator, text mining | PubMed |
| Microglial PICALM: A novel genetic driver and therapeutic target in vascular dementia. | Arch Gerontol Geriatr | 2026 | 42250393 | PubTator, text mining | PubMed |
| Shared Genetic Architecture Between Kidney Function and Alzheimer Disease Across Ancestries. | medRxiv | 2026 | 42006785 | PubTator, text mining | PubMed |
1 to 10 of 2,227
See all 2,227 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8301
GET https://conductscience.org/api/genes/v1/8301/patents