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Gene · 831

CAST: calpastatin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CAST: calpastatin. Genes, record 831. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/831

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Gene

Symbol
CAST
HGNC
Name
calpastatin
HGNC
NCBI Gene ID
831
NCBI Gene
HGNC ID
HGNC:1515
HGNC
Ensembl
ENSG00000153113, ENSG00000310517
NCBI Gene
Aliases
BS-17, MIR583HG, PLACK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P20810Calpastatin7080Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1439814P20810Espacenet
EP 4641201 A22025-10-296231P20810Espacenet
JP 2025517969 A2025-06-126231P20810Espacenet
JP 2025062604 A2025-04-1411215P20810Espacenet
JP 2025062604 A2025-04-1411218P20810Espacenet
US 11446398 B22022-09-2011215P20810Espacenet
US 11446398 B22022-09-2011218P20810Espacenet
JP 2022524081 A2022-04-27114186P20810Espacenet
JP 2022524081 A2022-04-27114189P20810Espacenet
JP 2019054813 A2019-04-11220249P20810Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,356

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCAST papersNewest fiscal year
P30CA034196Cancer Center Support (CORE) Grant82025
I01BX001262Hormonal Intervention Protects Axon-myelin to Promote Functional Recovery in SCI52025
P30CA016056Roswell Park Cancer Center Support Grant52025
P30CA021765Cancer Center Support Grant (CCSG)42025
F31HL167530Leveraging CRISPR RNA-guided DNA Transposases for Gene Insertion at the CFTR Locus32025
P30CA016086Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30DK020579Diabetes Research Center32025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease32025
P30EY026877Stanford Vision Research Core32025

1 to 10 of 1,356Source NIH's project files

See all 1,356 nih grants

Papers2,076

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Suppression of Calpain Attenuates Coxsackievirus B3-Induced Myocarditis by Regulating RIPK1/RIPK3/MLKL Pathway.J Cardiovasc Transl Res202642806174PubTator, text miningPubMed
Extra-synaptic localization of Bruchpilot in association with neurite outgrowth and cell motility in dissociated Drosophila embryonic cell cultures.J Neurogenet202642755035PubTator, text miningPubMed
De novo-engineered guide RNA-directed transposition with TnpB-family proteins.Mol Cell202642753721PubTator, text miningPubMed
Concomitant PLACK Syndrome, MYBPC3-Related Cardiomyopathy, and Nutritional Deficiency.Pediatr Dermatol202642742298PubTator, text miningPubMed
Decoding TnsC Filament Assembly in CRISPR-Associated Transposons Using Interpretable Deep Learning and Molecular Simulations.J Am Chem Soc202642701218PubTator, text miningPubMed
Transposon end recognition and pairing by I-F3 CRISPR-associated transposase.bioRxiv202642465468PubTator, text miningPubMed
Beef carcass electrical stimulation enhances Calpain-1 autolysis but not proteolysis.Meat Sci202642418871PubTator, text miningPubMed
DNA remodeling couples target recognition to directional transposition in a Tn7-like CAST.bioRxiv202642282781PubTator, text miningPubMed
Structural basis of RNA-guided DNA integration by type I CRISPR-associated transposases.bioRxiv202642239233PubTator, text miningPubMed
Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effects.Nat Commun202642225636PubTator, text miningPubMed

1 to 10 of 2,076

See all 2,076 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/831

GET https://conductscience.org/api/genes/v1/831/patents?page=2