Gene · 831
CAST: calpastatin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CAST: calpastatin. Genes, record 831. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/831
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P20810 | Calpastatin | 708 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 39814 | P20810 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6231 | P20810 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6231 | P20810 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 11215 | P20810 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 11218 | P20810 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 11215 | P20810 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 11218 | P20810 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 114186 | P20810 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 114189 | P20810 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 220249 | P20810 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,356
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CAST papers | Newest fiscal year |
|---|---|---|---|
| P30CA034196 | Cancer Center Support (CORE) Grant | 8 | 2025 |
| I01BX001262 | Hormonal Intervention Protects Axon-myelin to Promote Functional Recovery in SCI | 5 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 5 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| F31HL167530 | Leveraging CRISPR RNA-guided DNA Transposases for Gene Insertion at the CFTR Locus | 3 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30DK020579 | Diabetes Research Center | 3 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 3 | 2025 |
| P30EY026877 | Stanford Vision Research Core | 3 | 2025 |
1 to 10 of 1,356Source NIH's project files
See all 1,356 nih grantsPapers2,076
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Suppression of Calpain Attenuates Coxsackievirus B3-Induced Myocarditis by Regulating RIPK1/RIPK3/MLKL Pathway. | J Cardiovasc Transl Res | 2026 | 42806174 | PubTator, text mining | PubMed |
| Extra-synaptic localization of Bruchpilot in association with neurite outgrowth and cell motility in dissociated Drosophila embryonic cell cultures. | J Neurogenet | 2026 | 42755035 | PubTator, text mining | PubMed |
| De novo-engineered guide RNA-directed transposition with TnpB-family proteins. | Mol Cell | 2026 | 42753721 | PubTator, text mining | PubMed |
| Concomitant PLACK Syndrome, MYBPC3-Related Cardiomyopathy, and Nutritional Deficiency. | Pediatr Dermatol | 2026 | 42742298 | PubTator, text mining | PubMed |
| Decoding TnsC Filament Assembly in CRISPR-Associated Transposons Using Interpretable Deep Learning and Molecular Simulations. | J Am Chem Soc | 2026 | 42701218 | PubTator, text mining | PubMed |
| Transposon end recognition and pairing by I-F3 CRISPR-associated transposase. | bioRxiv | 2026 | 42465468 | PubTator, text mining | PubMed |
| Beef carcass electrical stimulation enhances Calpain-1 autolysis but not proteolysis. | Meat Sci | 2026 | 42418871 | PubTator, text mining | PubMed |
| DNA remodeling couples target recognition to directional transposition in a Tn7-like CAST. | bioRxiv | 2026 | 42282781 | PubTator, text mining | PubMed |
| Structural basis of RNA-guided DNA integration by type I CRISPR-associated transposases. | bioRxiv | 2026 | 42239233 | PubTator, text mining | PubMed |
| Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effects. | Nat Commun | 2026 | 42225636 | PubTator, text mining | PubMed |
1 to 10 of 2,076
See all 2,076 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/831
GET https://conductscience.org/api/genes/v1/831/patents?page=2