ConductScience.org, home

Gene · 833

CARS1: cysteinyl-tRNA synthetase 1

11 sourcesgene-search-2026-11-11-0.1.0

Download JSON
Cite this record

ConductScience Library. CARS1: cysteinyl-tRNA synthetase 1. Genes, record 833. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/833

On this page

Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
CARS1
HGNC
Name
cysteinyl-tRNA synthetase 1
HGNC
NCBI Gene ID
833
NCBI Gene
HGNC ID
HGNC:1493
HGNC
Ensembl
ENSG00000110619
NCBI Gene
Aliases
CARS, CYSRS, MCDDBH, MDBH, MGC:11246
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P49589Cysteine--tRNA ligase, cytoplasmic7480Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442750P49589Espacenet
EP 4650780 A22025-11-1911454P49589Espacenet
JP 2025523406 A2025-07-231P49589Espacenet
JP 2025517970 A2025-06-1211454P49589Espacenet
EP 4537838 A12025-04-161P49589Espacenet
JP 2024526483 A2024-07-192P49589Espacenet
KR 1020230169757 A2023-12-181P49589Espacenet
KR 1020230169758 A2023-12-181P49589Espacenet
US 11694765 B22023-07-04200P49589Espacenet
US 11446398 B22022-09-2021633P49589Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,921

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant832025
P30CA016672Cancer Center Support Grant312025
P50CA126752SPORE in Lymphoma262025
P30CA016520Abramson Cancer Center Support Grant242025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant192025
T32HL092332Training In Cell and Gene Therapy192025
P01CA214278Enhancing Chimeric Antigen Receptor T Cell Therapies for HematologicMalignancies: Beyond CART 19172025
P30CA021765Cancer Center Support Grant (CCSG)152025
P30CA076292Moffitt Cancer Center Support Grant132025
R01CA114536Novel synthetic receptors with improved antigen specificity and specificity for cancer therapy122025

1 to 10 of 1,921Source NIH's project files

See all 1,921 nih grants

Papers4,113

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42769515PubTator, text miningPubMed
42728543PubTator, text miningPubMed
42689985PubTator, text miningPubMed
42666236PubTator, text miningPubMed
42488656PubTator, text miningPubMed
42397933PubTator, text miningPubMed
42311665PubTator, text miningPubMed
42187436PubTator, text miningPubMed
42143019PubTator, text miningPubMed
42025164PubTator, text miningPubMed

1 to 10 of 4,113

See all 4,113 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/833

GET https://conductscience.org/api/genes/v1/833/patents?page=2