Gene · 8352
H3C3: H3 clustered histone 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. H3C3: H3 clustered histone 3. Genes, record 8352. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8352
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P68431 | Histone H3.1 | 136 | 544 | Ensembl, GeneID, HGNC |
Source UniProt
Patents238
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026506083 A | 2026-02-20 | 393 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49194 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49195 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49196 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49197 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49198 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49199 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49200 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49201 | P68431 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49202 | P68431 | Espacenet |
1 to 10 of 238
See all 238 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,240
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | H3C3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 24 | 2025 |
| P01CA096832 | NORMAL & NEOPLASTIC GROWTH IN THE BRAIN | 14 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 11 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 9 | 2025 |
| R01AI118891 | Viral modulation of epitranscriptomic mechanisms | 9 | 2025 |
| R35GM128661 | Investigating the roles of the H3.1-TSK/TONSL pathway during chromatin replication | 9 | 2025 |
| P50CA097257 | Brain Tumor SPORE Grant | 8 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 5 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 5 | 2025 |
1 to 10 of 1,240Source NIH's project files
See all 1,240 nih grantsPapers2,241
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| H3.1 Nucleosomes in Sepsis: A Biomarker, a Mechanism, or Both? | Crit Care Med | 2026 | 42622496 | PubTator, text mining | PubMed |
| Structural determination of human nucleosomes reconstituted by the ExACT platform. | bioRxiv | 2026 | 42620049 | PubTator, text mining | PubMed |
| Predictive performance of kinetic eGFR, midregional proadrenomedullin, and H3.1 nucleosomes for acute kidney disease in sepsis: a secondary analysis of a large multicentre randomized controlled trial. | J Intensive Care | 2026 | 42618952 | PubTator, text mining | PubMed |
| H3.1 Nucleosomes to Predict Renal Replacement Therapy and Mortality in Sepsis-A Secondary Analysis of the SISPCT Randomized Control Trial. | Crit Care Med | 2026 | 42545097 | PubTator, text mining | PubMed |
| Neutrophil extracellular traps induced by a monoclonal anti-phosphatidylserine/prothrombin antibody activate platelets in vitro. | Exp Mol Pathol | 2026 | 42531670 | PubTator, text mining | PubMed |
| Development of the cf-MMSP Assay for Enhanced Analytical Sensitivity of Methylated DNA in Breast Cancer Liquid Biopsy. | Cancer Epidemiol Biomarkers Prev | 2026 | 42334419 | PubTator, text mining | PubMed |
| CD177+ Neutrophils Promote Endothelial Senescence Through Extracellular Traps in Behçet Disease. | Arthritis Rheumatol | 2026 | 42109254 | PubTator, text mining | PubMed |
| MPA-KCro: Antibody-Free Crotonylome Profiling via 2‑Mercaptophosphonic Acid Michael Addition and Titanium(IV)-Immobilized Metal Affinity Chromatography Enrichment. | JACS Au | 2026 | 42063823 | PubTator, text mining | PubMed |
| Basal ganglia glioblastoma with lung adenocarcinoma tumor-to-tumor metastasis and atypical early imaging presentation: illustrative case. | J Neurosurg Case Lessons | 2026 | 41941839 | PubTator, text mining | PubMed |
| Prevalence and Clinicoradiopathological Characterization of H3 K27-Altered Diffuse Midline Gliomas in Adults-A Retrospective Observational Study. | Pathophysiology | 2026 | 41893372 | PubTator, text mining | PubMed |
1 to 10 of 2,241
See all 2,241 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8352
GET https://conductscience.org/api/genes/v1/8352/patents?page=2