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Gene · 8352

H3C3: H3 clustered histone 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. H3C3: H3 clustered histone 3. Genes, record 8352. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8352

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Gene

Symbol
H3C3
HGNC
Name
H3 clustered histone 3
HGNC
NCBI Gene ID
8352
NCBI Gene
HGNC ID
HGNC:4768
HGNC
Ensembl
ENSG00000287080
NCBI Gene
Aliases
H3.1, H3/c, H3FC, HIST1H3C
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P68431Histone H3.1136544Ensembl, GeneID, HGNC

Source UniProt

Patents238

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026506083 A2026-02-20393P68431Espacenet
JP 2026004568 A2026-01-1449194P68431Espacenet
JP 2026004568 A2026-01-1449195P68431Espacenet
JP 2026004568 A2026-01-1449196P68431Espacenet
JP 2026004568 A2026-01-1449197P68431Espacenet
JP 2026004568 A2026-01-1449198P68431Espacenet
JP 2026004568 A2026-01-1449199P68431Espacenet
JP 2026004568 A2026-01-1449200P68431Espacenet
JP 2026004568 A2026-01-1449201P68431Espacenet
JP 2026004568 A2026-01-1449202P68431Espacenet

1 to 10 of 238

See all 238 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,240

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleH3C3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant242025
P01CA096832NORMAL & NEOPLASTIC GROWTH IN THE BRAIN142025
P30CA016672Cancer Center Support Grant112025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center112025
P30CA021765Cancer Center Support Grant (CCSG)92025
R01AI118891Viral modulation of epitranscriptomic mechanisms92025
R35GM128661Investigating the roles of the H3.1-TSK/TONSL pathway during chromatin replication92025
P50CA097257Brain Tumor SPORE Grant82025
P30CA006973Regional Oncology Research Center52025
P30CA010815Consolidated Basic Cancer Research Program52025

1 to 10 of 1,240Source NIH's project files

See all 1,240 nih grants

Papers2,241

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
H3.1 Nucleosomes in Sepsis: A Biomarker, a Mechanism, or Both?Crit Care Med202642622496PubTator, text miningPubMed
Structural determination of human nucleosomes reconstituted by the ExACT platform.bioRxiv202642620049PubTator, text miningPubMed
Predictive performance of kinetic eGFR, midregional proadrenomedullin, and H3.1 nucleosomes for acute kidney disease in sepsis: a secondary analysis of a large multicentre randomized controlled trial.J Intensive Care202642618952PubTator, text miningPubMed
H3.1 Nucleosomes to Predict Renal Replacement Therapy and Mortality in Sepsis-A Secondary Analysis of the SISPCT Randomized Control Trial.Crit Care Med202642545097PubTator, text miningPubMed
Neutrophil extracellular traps induced by a monoclonal anti-phosphatidylserine/prothrombin antibody activate platelets in vitro.Exp Mol Pathol202642531670PubTator, text miningPubMed
Development of the cf-MMSP Assay for Enhanced Analytical Sensitivity of Methylated DNA in Breast Cancer Liquid Biopsy.Cancer Epidemiol Biomarkers Prev202642334419PubTator, text miningPubMed
CD177+ Neutrophils Promote Endothelial Senescence Through Extracellular Traps in Behçet Disease.Arthritis Rheumatol202642109254PubTator, text miningPubMed
MPA-KCro: Antibody-Free Crotonylome Profiling via 2‑Mercaptophosphonic Acid Michael Addition and Titanium(IV)-Immobilized Metal Affinity Chromatography Enrichment.JACS Au202642063823PubTator, text miningPubMed
Basal ganglia glioblastoma with lung adenocarcinoma tumor-to-tumor metastasis and atypical early imaging presentation: illustrative case.J Neurosurg Case Lessons202641941839PubTator, text miningPubMed
Prevalence and Clinicoradiopathological Characterization of H3 K27-Altered Diffuse Midline Gliomas in Adults-A Retrospective Observational Study.Pathophysiology202641893372PubTator, text miningPubMed

1 to 10 of 2,241

See all 2,241 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8352

GET https://conductscience.org/api/genes/v1/8352/patents?page=2