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SESN2: sestrin 2
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Gene · 83667

Papers1,838

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,838

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TitleJournalYearPMIDFound bySource
An immune-adaptive 3D-printed scaffold promotes endogenous osteogenesis by engineered macrophage capture traps.Biomaterials202742607641PubTator, text miningPubMed
Evaluation of Clusterin, Sestrin-2, Oxidative Stress, and Inflammatory Indices in Patients with Alzheimer's Disease Dementia.Brain Sci202642793402PubTator, text miningPubMed
Correlation analysis of serum FGF9, Sestrin2 and HBDH with the severity of sepsis.J Med Biochem202642780906PubTator, text miningPubMed
CBX3 aggravates nucleus pulposus cell apoptosis and extracellular matrix degradation in vitro via repressing SESN2-mediated mitophagy in an H3K9me3-dependent manner.Mol Biol Rep202642776360PubTator, text miningPubMed
D-amino acid prodrug DLMEH activates mTORC1 via Sestrin2 to restore muscle protein synthesis in sarcopenia.Mol Ther202642723280PubTator, text miningPubMed
CD84 expression stratifies venetoclax response and reveals a targetable vulnerability in resistant acute myeloid leukemia.Exp Hematol Oncol202642706583PubTator, text miningPubMed
Age and sex modify the association between plasma Sestrin2 and bone mineral density: a cross-sectional study.JBMR Plus202642689222PubTator, text miningPubMed
Evaluation of the Nrf2-Keap1 and Sestrin-2 Pathways in the Serum of Patients with Hidradenitis Suppurativa.Medicina (Kaunas)202642654508PubTator, text miningPubMed
SIRT2 deacylase modulators control B cell metabolic reprogramming in EBV infection and mitogenic activation.Proc Natl Acad Sci U S A202642636358PubTator, text miningPubMed
CqSESN2 suppresses WSSV infection via the CqNrf2 antioxidant pathway in Cherax quadricarinatus.Fish Shellfish Immunol202642628590PubTator, text miningPubMed
ATF4 activates a transcriptional program that chronically suppresses mTOR activity and promotes neurodegeneration in Parkinson disease models.Cell Rep202642599806PubTator, text miningPubMed
CDCA4 Promotes Lipid Metabolism in Triple-Negative Breast Cancer Through Activation of the SESN2/mTOR/SREBP1 Pathway.Cancers (Basel)202642588732PubTator, text miningPubMed
Chiisanoside Ameliorates d-Galactose-Induced Age-Related Hearing Loss by Modulating Autophagy and Ferroptosis via the SESN2/AMPK Axis.J Agric Food Chem202642584111PubTator, text miningPubMed
High-resolution mapping of chromatin conformation in HBeAg-treated macrophage provides insights into pathogenesis of HBV-related liver diseases.Front Immunol202642534908PubTator, text miningPubMed
Investigating the Role of Oxidative Stress Parameters in the Spectrum of Preschool Anxiety Disorders.Early Interv Psychiatry202642527997PubTator, text miningPubMed
Effects of Sestrin2 on Angiogenesis of Human Umbilical Vein Endothelial Cells in Hypoxia Environment.Stem Cells Dev202642517294PubTator, text miningPubMed
Microvesicle-Derived Redox Signatures as Mediators of Endothelial Dysfunction in Diabetes.Int J Mol Sci202642450273PubTator, text miningPubMed
Anti-myeloma mechanisms of the selective NF-κB inhibitor QNZ.Mol Ther Oncol202642440520PubTator, text miningPubMed
Sestrin-2: a new biomarker for type 2 Diabetes Mellitus and Insulin resistance.J Diabetes Metab Disord202642422115PubTator, text miningPubMed
Combination of sitagliptin and mangiferin mitigates testicular damage induced by paclitaxel via mediating Sestrin2/Keap1/Nrf2 signaling pathway.Mol Cell Biochem202642384342PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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