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Gene · 83716

CRISPLD2: cysteine rich secretory protein LCCL domain containing 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CRISPLD2: cysteine rich secretory protein LCCL domain containing 2. Genes, record 83716. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/83716

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Gene

Symbol
CRISPLD2
HGNC
Name
cysteine rich secretory protein LCCL domain containing 2
HGNC
NCBI Gene ID
83716
NCBI Gene
HGNC ID
HGNC:25248
HGNC
Ensembl
ENSG00000103196
NCBI Gene
Aliases
CRISP11, DKFZP434B044, LCRISP2, LGL1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H0B8Cysteine-rich secretory protein LCCL domain-containing 24970Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442738Q9H0B8Espacenet
EP 4650780 A22025-11-192068Q9H0B8Espacenet
JP 2025147176 A2025-10-063538Q9H0B8Espacenet
JP 2025529142 A2025-09-046014Q9H0B8Espacenet
US 12371689 B22025-07-296014Q9H0B8Espacenet
JP 2025517970 A2025-06-122068Q9H0B8Espacenet
JP 2025032204 A2025-03-1126815Q9H0B8Espacenet
JP 2025028160 A2025-02-283538Q9H0B8Espacenet
KR 1020250010750 A2025-01-213538Q9H0B8Espacenet
EP 4461818 A22024-11-1326815Q9H0B8Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,096

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCRISPLD2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant42025
P30CA036727Buffett Cancer Center Support Grant42025
P30ES013508Center of Excellence in Environmental Toxicology42025
P20GM103476Mississippi INBRE32025
IK6BX004607BLR&D Research Career Scientist Award Application22025
P20GM113126Nebraska Center for Integrated Biomolecular Communication (CIBC)22025
P20GM113226Hepatobiology and Toxicology COBRE22025
P30AG072979Penn Alzheimer's Disease Research Center (ADRC)22025
P30CA014195Cancer Center Support Grant (CCSG)22025
P30CA016087Cancer Center Support Grant22025

1 to 10 of 1,096Source NIH's project files

See all 1,096 nih grants

Papers1,655

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of Cancer-associated Fibroblasts-specific ncRNA-mRNA/Protein Regulatory Axes in Prostate Cancer.Anticancer Res202642823170PubTator, text miningPubMed
Identification of GOT1, OAF, XPNPEP2, CRISPLD2, and RPS21 as Sorafenib-Treatment-Associated Candidate Biomarkers for Hepatocellular Carcinoma.Curr Med Chem202642634552PubTator, text miningPubMed
Infantile exocrine pancreatic insufficiency due to a homozygous SPINK1 pathogenic variant in two siblings: A case report.JPGN Rep202642110147PubTator, text miningPubMed
Microtubules guide Aurora B substrate geometries for accurate chromosome segregation.Sci Adv202641880487PubTator, text miningPubMed
Nanostructured electrochemical biosensor modified with a plant-derived protein for serine protease detection in prostate cancer.Anal Biochem202641812858PubTator, text miningPubMed
NOTCH3 CADASIL Variant Receptor Aggregation Requires NOTCH3 Wild-Type Receptors: Identification of Highly Selective Inhibitors That Block the Process.FASEB J202641806331PubTator, text miningPubMed
Wheat Allergy in the Era of Precision Medicine: From Novel Molecular Markers to New Therapeutic Perspectives.Int J Mol Sci202641751854PubTator, text miningPubMed
Advancing Gene Therapy for Pancreatitis: From Genetic Insights to Clinical Translation.Research (Wash D C)202641743849PubTator, text miningPubMed
RNA cargo profiling of muscle extracellular vesicles identifies candidate biomarkers of disease activity and muscle degeneration in FSHD.J Transl Med202641742280PubTator, text miningPubMed
Common Biomarkers in Chronic Obstructive Pulmonary Disease and Bronchopulmonary Dysplasia: A Narrative Review of an Intriguing Interplay.Int J Mol Sci202641683842PubTator, text miningPubMed

1 to 10 of 1,655

See all 1,655 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/83716

GET https://conductscience.org/api/genes/v1/83716/patents?page=2