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EIF2A: eukaryotic translation initiation factor 2A

1 protein, 25 patents, 0 drugs, 0 trials, 6,477 NIH grants and 12,424 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolEIF2AHGNC
Nameeukaryotic translation initiation factor 2AHGNC
NCBI Gene ID83939NCBI Gene
HGNC IDHGNC:3254HGNC
EnsemblENSG00000144895NCBI Gene
AliasesCDA02, EIF-2A, MST089, MSTP004, MSTP089NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9BY44Eukaryotic translation initiation factor 2A5851Ensembl, GeneID, HGNCUniProt

Patents 25

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445463Q9BY44Espacenet
EP 4650780 A22025-11-1914067Q9BY44Espacenet
JP 2025517970 A2025-06-1214067Q9BY44Espacenet
US 11446398 B22022-09-2028626Q9BY44Espacenet
JP 2022524081 A2022-04-27131597Q9BY44Espacenet
US 11078247 B22021-08-033450Q9BY44Espacenet
US 10729784 B22020-08-0416Q9BY44Espacenet
WO 2020043864 A12020-03-05775Q9BY44Espacenet
JP 2019054813 A2019-04-11225898Q9BY44Espacenet
US 10207009 B22019-02-1916Q9BY44Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6477

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant542,025NIH's project files
ZIAHD001010Mechanism and Regulation of Eukaryotic Protein Synthesis282,025NIH's project files
R01DK060596Translational control by nutrients262,025NIH's project files
P30CA008748Cancer Center Support Grant242,025NIH's project files
P30CA047904Cancer Center Support Grant222,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)182,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant182,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program162,025NIH's project files
P30ES006694Southwest Environmental Health Sciences Center162,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant152,025NIH's project files

Papers 12424

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818380PubTator, text miningPubMed
42818268PubTator, text miningPubMed
42813994PubTator, text miningPubMed
42806587PubTator, text miningPubMed
42806331PubTator, text miningPubMed
42804747PubTator, text miningPubMed
42802286PubTator, text miningPubMed
42800448PubTator, text miningPubMed
42800308PubTator, text miningPubMed
42794732PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license