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CASP7: caspase 7

1 protein, 152 patents, 1 drug, 11 trials, 4,737 NIH grants and 12,974 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCASP7HGNC
Namecaspase 7HGNC
NCBI Gene ID840NCBI Gene
HGNC IDHGNC:1508HGNC
EnsemblENSG00000165806NCBI Gene
AliasesCASP-7, CMH-1, ICE-LAP3, LICE2, MCH3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P55210Caspase-730347Ensembl, GeneID, HGNCUniProt

Patents 152

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4774398 A12026-07-1553P55210Espacenet
US 12539325 B22026-02-0324P55210Espacenet
EP 4650780 A22025-11-193887P55210Espacenet
EP 4640849 A22025-10-29502P55210Espacenet
EP 4641201 A22025-10-293466P55210Espacenet
JP 2025147176 A2025-10-0616533P55210Espacenet
JP 2025519096 A2025-06-24502P55210Espacenet
JP 2025517969 A2025-06-123466P55210Espacenet
JP 2025517970 A2025-06-123887P55210Espacenet
JP 2025062604 A2025-04-1412279P55210Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
EMRICASANCHEMBL197672Caspase inhibitorINHIBITORChEMBL

Trials 11

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04803227EMRICASANPHASE1ClinicalTrials.gov
NCT03205345EMRICASANPHASE2ClinicalTrials.gov
NCT02686762EMRICASANPHASE2ClinicalTrials.gov
NCT02230683EMRICASANPHASE22016-12-21ClinicalTrials.gov
NCT02230670EMRICASANPHASE22017-07-05ClinicalTrials.gov
NCT02138253EMRICASANPHASE22019-12-11ClinicalTrials.gov
NCT02077374EMRICASANPHASE22016-07-21ClinicalTrials.gov
NCT01937130EMRICASANPHASE22016-04-11ClinicalTrials.gov
NCT01912404EMRICASANPHASE22016-11-04ClinicalTrials.gov
NCT01653899EMRICASANPHASE1/PHASE2ClinicalTrials.gov

NIH grants 4737

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant902,025NIH's project files
P30CA008748Cancer Center Support Grant272,025NIH's project files
P30CA016058Cancer Center Support Grant212,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant162,025NIH's project files
R01AI124346Innate immune signaling and stress response162,025NIH's project files
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation152,025NIH's project files
R35CA253095Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancer142,025NIH's project files
P20GM103434West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)132,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028132,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase122,025NIH's project files

Papers 12974

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42793131PubTator, text miningPubMed
42792910PubTator, text miningPubMed
42769600PubTator, text miningPubMed
42768102PubTator, text miningPubMed
42739743PubTator, text miningPubMed
42722901PubTator, text miningPubMed
42706828PubTator, text miningPubMed
42677111PubTator, text miningPubMed
42674249PubTator, text miningPubMed
42631906PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license