ConductScience.org, home

Gene · 8411

EEA1: early endosome antigen 1

11 sourcesgene-search-2026-11-11-0.1.0

Download JSON
Cite this record

ConductScience Library. EEA1: early endosome antigen 1. Genes, record 8411. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/8411

On this page

Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
EEA1
HGNC
Name
early endosome antigen 1
HGNC
NCBI Gene ID
8411
NCBI Gene
HGNC ID
HGNC:3185
HGNC
Ensembl
ENSG00000102189
NCBI Gene
Aliases
MST105, MSTP105, ZFYVE2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15075Early endosome antigen 11,4114Ensembl, GeneID, HGNC

Source UniProt

Patents12

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195144Q15075Espacenet
EP 4641201 A22025-10-294742Q15075Espacenet
JP 2025517969 A2025-06-124742Q15075Espacenet
JP 2025517970 A2025-06-125144Q15075Espacenet
US 11446398 B22022-09-2026474Q15075Espacenet
KR 1020220125424 A2022-09-1410Q15075Espacenet
JP 2022524081 A2022-04-27129445Q15075Espacenet
US 10751370 B22020-08-2541Q15075Espacenet
JP 2017121240 A2017-07-1350042Q15075Espacenet
JP 2015518704 A2015-07-0650042Q15075Espacenet

1 to 10 of 12

See all 12 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants3,604

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant202025
R01DA012864Mechanisms and Cellular Function of Opioid Receptor Endocytosis142025
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System132025
P30CA036727Buffett Cancer Center Support Grant92025
P30CA008748Cancer Center Support Grant82025
P30DA018343Yale/NIDA Neuroproteomics Center82025
P30DK058404Molecular and Cellular Basis for Digestive Diseases82025
R01DA014204Regulation of Dopamine Transporter by Trafficking82025
R01NS083378Organization and Function of Neuronal Endosomes82025
P30CA118100University of New Mexico Cancer Center Support Grant72025

1 to 10 of 3,604Source NIH's project files

See all 3,604 nih grants

Papers4,397

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42695012PubTator, text miningPubMed
42566996PubTator, text miningPubMed
42481375PubTator, text miningPubMed
42389534PubTator, text miningPubMed
42326826PubTator, text miningPubMed
42323615PubTator, text miningPubMed
42234594PubTator, text miningPubMed
42233622PubTator, text miningPubMed
42165362PubTator, text miningPubMed
42149354PubTator, text miningPubMed

1 to 10 of 4,397

See all 4,397 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8411

GET https://conductscience.org/api/genes/v1/8411/patents