Gene · 84126
ATRIP: ATR interacting protein
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ATRIP: ATR interacting protein. Genes, record 84126. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84126
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8WXE1 | ATR-interacting protein | 791 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents25
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38510 | Q8WXE1 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5476 | Q8WXE1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5088 | Q8WXE1 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5088 | Q8WXE1 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5476 | Q8WXE1 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7853 | Q8WXE1 | Espacenet |
| US 11976334 B2 | 2024-05-07 | 117 | Q8WXE1 | Espacenet |
| US 11708396 B2 | 2023-07-25 | 2078 | Q8WXE1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 7853 | Q8WXE1 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 110824 | Q8WXE1 | Espacenet |
1 to 10 of 25
See all 25 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,129
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ATRIP papers | Newest fiscal year |
|---|---|---|---|
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 26 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 20 | 2025 |
| T32CA009582 | Biochemical and Chemical Training for Cancer Research | 15 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 8 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 8 | 2025 |
| T32ES007028 | Training Program in Environmental Toxicology | 8 | 2025 |
| R01CA142861 | Renewal: HPV and the DNA Damage Response | 7 | 2025 |
| R01ES016486 | Regulation of the DNA Damage Response | 6 | 2025 |
| R01GM116616 | Analysis of the Replication Stress Response | 6 | 2025 |
1 to 10 of 1,129Source NIH's project files
See all 1,129 nih grantsPapers1,279
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| MCPH1 and DNA Damage Response Pathway Genes as Candidate Susceptibility Loci in Hereditary Breast Cancer. | Diagnostics (Basel) | 2026 | 42793752 | PubTator, text mining | PubMed |
| Capturing ATR-ATRIP in the act of activation. | Nat Struct Mol Biol | 2026 | 42754754 | PubTator, text mining | PubMed |
| Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR-ATRIP. | Nat Struct Mol Biol | 2026 | 42754753 | PubTator, text mining | PubMed |
| SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA-PKcs/CHK1 replicative checkpoint to inhibit cell growth in non-small cell lung cancer. | Mol Oncol | 2026 | 42751865 | PubTator, text mining | PubMed |
| New Roles of Chk1 in Spindle Formation and Genome Integrity. | Biology (Basel) | 2026 | 42510653 | PubTator, text mining | PubMed |
| Structural mechanism of TOPBP1 activating the ATR-ATRIP replication checkpoint kinase. | Nat Struct Mol Biol | 2026 | 42493622 | PubTator, text mining | PubMed |
| Identification of dual-targeting PROTACs for ataxia telangiectasia and RAD3-related and aurora kinase A as chemo-sensitizers for leukemia cells. | Eur J Med Chem | 2026 | 42462624 | PubTator, text mining | PubMed |
| Library-based, multiplexed strategy for mapping protein interaction networks via crosslinking. | BMC Biotechnol | 2026 | 42304341 | PubTator, text mining | PubMed |
| Germline ATRIP variants and the risk of ovarian cancer. | Genet Med | 2026 | 42118082 | PubTator, text mining | PubMed |
| An updated view on lagging strand DNA replication: implications for the replication stress response. | Cell Cycle | 2026 | 41865289 | PubTator, text mining | PubMed |
1 to 10 of 1,279
See all 1,279 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/84126
GET https://conductscience.org/api/genes/v1/84126/patents?page=2