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Gene · 84126

ATRIP: ATR interacting protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATRIP: ATR interacting protein. Genes, record 84126. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84126

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Gene

Symbol
ATRIP
HGNC
Name
ATR interacting protein
HGNC
NCBI Gene ID
84126
NCBI Gene
HGNC ID
HGNC:33499
HGNC
Ensembl
ENSG00000164053
NCBI Gene
Aliases
FLJ12343, MGC20625, MGC21482, MGC26740
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8WXE1ATR-interacting protein79111Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438510Q8WXE1Espacenet
EP 4650780 A22025-11-195476Q8WXE1Espacenet
EP 4641201 A22025-10-295088Q8WXE1Espacenet
JP 2025517969 A2025-06-125088Q8WXE1Espacenet
JP 2025517970 A2025-06-125476Q8WXE1Espacenet
JP 2025062604 A2025-04-147853Q8WXE1Espacenet
US 11976334 B22024-05-07117Q8WXE1Espacenet
US 11708396 B22023-07-252078Q8WXE1Espacenet
US 11446398 B22022-09-207853Q8WXE1Espacenet
JP 2022524081 A2022-04-27110824Q8WXE1Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,129

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATRIP papersNewest fiscal year
P01CA092584Structural Cell Biology of DNA Repair Machines262025
P30CA016672Cancer Center Support Grant202025
T32CA009582Biochemical and Chemical Training for Cancer Research152025
P30CA008748Cancer Center Support Grant112025
P30CA068485Cancer Center Support Grant82025
P30ES010126UNC Center for Environmental Health and Susceptibility82025
T32ES007028Training Program in Environmental Toxicology82025
R01CA142861Renewal: HPV and the DNA Damage Response72025
R01ES016486Regulation of the DNA Damage Response62025
R01GM116616Analysis of the Replication Stress Response62025

1 to 10 of 1,129Source NIH's project files

See all 1,129 nih grants

Papers1,279

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
MCPH1 and DNA Damage Response Pathway Genes as Candidate Susceptibility Loci in Hereditary Breast Cancer.Diagnostics (Basel)202642793752PubTator, text miningPubMed
Capturing ATR-ATRIP in the act of activation.Nat Struct Mol Biol202642754754PubTator, text miningPubMed
Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR-ATRIP.Nat Struct Mol Biol202642754753PubTator, text miningPubMed
SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA-PKcs/CHK1 replicative checkpoint to inhibit cell growth in non-small cell lung cancer.Mol Oncol202642751865PubTator, text miningPubMed
New Roles of Chk1 in Spindle Formation and Genome Integrity.Biology (Basel)202642510653PubTator, text miningPubMed
Structural mechanism of TOPBP1 activating the ATR-ATRIP replication checkpoint kinase.Nat Struct Mol Biol202642493622PubTator, text miningPubMed
Identification of dual-targeting PROTACs for ataxia telangiectasia and RAD3-related and aurora kinase A as chemo-sensitizers for leukemia cells.Eur J Med Chem202642462624PubTator, text miningPubMed
Library-based, multiplexed strategy for mapping protein interaction networks via crosslinking.BMC Biotechnol202642304341PubTator, text miningPubMed
Germline ATRIP variants and the risk of ovarian cancer.Genet Med202642118082PubTator, text miningPubMed
An updated view on lagging strand DNA replication: implications for the replication stress response.Cell Cycle202641865289PubTator, text miningPubMed

1 to 10 of 1,279

See all 1,279 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/84126

GET https://conductscience.org/api/genes/v1/84126/patents?page=2