Gene · 84142
ABRAXAS1: abraxas 1, BRCA1 A complex subunit
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABRAXAS1: abraxas 1, BRCA1 A complex subunit. Genes, record 84142. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84142
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q6UWZ7 | BRCA1-A complex subunit Abraxas 1 | 409 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 10319 | Q6UWZ7 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10632 | Q6UWZ7 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 67 | Q6UWZ7 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6323 | Q6UWZ7 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6323 | Q6UWZ7 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10632 | Q6UWZ7 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10319 | Q6UWZ7 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 67 | Q6UWZ7 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 67 | Q6UWZ7 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 74 | Q6UWZ7 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants391
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABRAXAS1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 4 | 2025 |
| P50CA116201 | Mayo Clinic Breast Cancer SPORE | 4 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 3 | 2025 |
| R01CA198279 | Shaping DNA Damage Response Networks Via Histone H2A Variants | 3 | 2025 |
| K12CA184746 | MSK Paul Calabresi Career Development Award for Clinical Oncology | 2 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 2 | 2025 |
| P30CA016520 | Abramson Cancer Center Support Grant | 2 | 2025 |
| P30CA056036 | Translational Research in Cancer | 2 | 2025 |
1 to 10 of 391Source NIH's project files
See all 391 nih grantsPapers460
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers. | Nat Commun | 2025 | 41006228 | PubTator, text mining | PubMed |
| Mutation characteristics of cancer susceptibility genes in Chinese ovarian cancer patients. | Front Oncol | 2024 | 38817903 | PubTator, text mining | PubMed |
| Histologic patterns in prostatic adenocarcinoma are not predictive of mutations in the homologous recombination repair pathway. | Hum Pathol | 2024 | 38278448 | PubTator, text mining | PubMed |
| Prevalence and Distribution of MUTYH Pathogenic Variants, Is There a Relation with an Increased Risk of Breast Cancer? | Cancers (Basel) | 2024 | 38254803 | PubTator, text mining | PubMed |
| A novel targeted NGS panel identifies numerous homologous recombination deficiency (HRD)-associated gene mutations in addition to known BRCA mutations. | Diagn Pathol | 2024 | 38184614 | PubTator, text mining | PubMed |
| The ubiquitin codes in cellular stress responses. | Protein Cell | 2024 | 37470788 | PubTator, text mining | PubMed |
| Assessing the Phenotype of a Homologous Recombination Deficiency Using High Resolution Array-Based Comparative Genome Hybridization in Ovarian Cancer. | Int J Mol Sci | 2023 | 38139296 | PubTator, text mining | PubMed |
| Early-Onset Ovarian Cancer <30 Years: What Do We Know about Its Genetic Predisposition? | Int J Mol Sci | 2023 | 38069345 | PubTator, text mining | PubMed |
| Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer. | Cancers (Basel) | 2023 | 38067280 | PubTator, text mining | PubMed |
| Cancer Risk Factors in Southern Brazil: Report of a Comprehensive, Matched Case-Control Study. | JCO Glob Oncol | 2023 | 38060977 | PubTator, text mining | PubMed |
1 to 10 of 460
See all 460 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/84142
GET https://conductscience.org/api/genes/v1/84142/patents?page=2