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Gene · 84142

ABRAXAS1: abraxas 1, BRCA1 A complex subunit

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ABRAXAS1: abraxas 1, BRCA1 A complex subunit. Genes, record 84142. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84142

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Gene

Symbol
ABRAXAS1
HGNC
Name
abraxas 1, BRCA1 A complex subunit
HGNC
NCBI Gene ID
84142
NCBI Gene
HGNC ID
HGNC:25829
HGNC
Ensembl
ENSG00000163322
NCBI Gene
Aliases
ABRA1, ABRAXAS, CCDC98, FAM175A, FLJ13614
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6UWZ7BRCA1-A complex subunit Abraxas 140910Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910319Q6UWZ7Espacenet
EP 4641201 A22025-10-2910632Q6UWZ7Espacenet
JP 2025147176 A2025-10-0667Q6UWZ7Espacenet
JP 2025529142 A2025-09-046323Q6UWZ7Espacenet
US 12371689 B22025-07-296323Q6UWZ7Espacenet
JP 2025517969 A2025-06-1210632Q6UWZ7Espacenet
JP 2025517970 A2025-06-1210319Q6UWZ7Espacenet
JP 2025028160 A2025-02-2867Q6UWZ7Espacenet
KR 1020250010750 A2025-01-2167Q6UWZ7Espacenet
JP 2024109657 A2024-08-1474Q6UWZ7Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants391

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleABRAXAS1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant112025
P30CA016672Cancer Center Support Grant62025
P30CA006973Regional Oncology Research Center42025
P50CA116201Mayo Clinic Breast Cancer SPORE42025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
R01CA198279Shaping DNA Damage Response Networks Via Histone H2A Variants32025
K12CA184746MSK Paul Calabresi Career Development Award for Clinical Oncology22025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA016520Abramson Cancer Center Support Grant22025
P30CA056036Translational Research in Cancer22025

1 to 10 of 391Source NIH's project files

See all 391 nih grants

Papers460

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers.Nat Commun202541006228PubTator, text miningPubMed
Mutation characteristics of cancer susceptibility genes in Chinese ovarian cancer patients.Front Oncol202438817903PubTator, text miningPubMed
Histologic patterns in prostatic adenocarcinoma are not predictive of mutations in the homologous recombination repair pathway.Hum Pathol202438278448PubTator, text miningPubMed
Prevalence and Distribution of MUTYH Pathogenic Variants, Is There a Relation with an Increased Risk of Breast Cancer?Cancers (Basel)202438254803PubTator, text miningPubMed
A novel targeted NGS panel identifies numerous homologous recombination deficiency (HRD)-associated gene mutations in addition to known BRCA mutations.Diagn Pathol202438184614PubTator, text miningPubMed
The ubiquitin codes in cellular stress responses.Protein Cell202437470788PubTator, text miningPubMed
Assessing the Phenotype of a Homologous Recombination Deficiency Using High Resolution Array-Based Comparative Genome Hybridization in Ovarian Cancer.Int J Mol Sci202338139296PubTator, text miningPubMed
Early-Onset Ovarian Cancer <30 Years: What Do We Know about Its Genetic Predisposition?Int J Mol Sci202338069345PubTator, text miningPubMed
Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer.Cancers (Basel)202338067280PubTator, text miningPubMed
Cancer Risk Factors in Southern Brazil: Report of a Comprehensive, Matched Case-Control Study.JCO Glob Oncol202338060977PubTator, text miningPubMed

1 to 10 of 460

See all 460 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/84142

GET https://conductscience.org/api/genes/v1/84142/patents?page=2