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Gene · 84148

KAT8: lysine acetyltransferase 8

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KAT8: lysine acetyltransferase 8. Genes, record 84148. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84148

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Gene

Symbol
KAT8
HGNC
Name
lysine acetyltransferase 8
HGNC
NCBI Gene ID
84148
NCBI Gene
HGNC ID
HGNC:17933
HGNC
Ensembl
ENSG00000103510
NCBI Gene
Aliases
FLJ14040, LIGOWS, MOF, MYST1, ZC2HC8, hMOF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H7Z6Histone acetyltransferase KAT845843Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19462Q9H7Z6Espacenet
EP 4641201 A22025-10-29322Q9H7Z6Espacenet
JP 2025147176 A2025-10-0615197Q9H7Z6Espacenet
JP 2025517969 A2025-06-12322Q9H7Z6Espacenet
JP 2025517970 A2025-06-12462Q9H7Z6Espacenet
JP 2025028160 A2025-02-2815197Q9H7Z6Espacenet
KR 1020250010750 A2025-01-2115197Q9H7Z6Espacenet
JP 2024109657 A2024-08-1415036Q9H7Z6Espacenet
US 11446398 B22022-09-2042436Q9H7Z6Espacenet
US 11446398 B22022-09-2042439Q9H7Z6Espacenet

1 to 10 of 26

See all 26 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,509

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKAT8 papersNewest fiscal year
P30CA010815Consolidated Basic Cancer Research Program82025
P30CA016672Cancer Center Support Grant82025
ZIABC011488Targeting Cancer Through Modifications and Metabolism72025
P30CA046934University of Colorado Cancer Center Support Grant62025
P30CA008748Cancer Center Support Grant52025
P30ES013508Center of Excellence in Environmental Toxicology52025
P42ES004705Toxic substances in the environment52025
R35GM118090Molecular Mechanisms, Pathways and Inhibition of Acetyl-Transfer Reactions52025
P30CA076292Moffitt Cancer Center Support Grant42025
P30CA086862Cancer Center Support Grant42025

1 to 10 of 1,509Source NIH's project files

See all 1,509 nih grants

Papers2,655

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Boosting Photoelectrochemical Water Oxidation of BiVO4 Photoanodes With an Iron-Based Metal-Organic Framework as a Hole Transport Layer.Angew Chem Int Ed Engl202642815931PubTator, text miningPubMed
Multimodal Transformer for Sample-Aware Prediction of Metal-Organic Framework Properties.ACS Cent Sci202642799131PubTator, text miningPubMed
Facilely Synthesis of MOF-Derived Nickel Phyllosilicate Nanosheet Assembly and Its Application in Robust, Toughened and Wear-Resistant Epoxy Composites.Polymers (Basel)202642797115PubTator, text miningPubMed
The KAT8-CDK1 K33 acetylation axis drives doxorubicin resistance by suppressing ferroptosis and apoptosis in breast cancer.Cell Death Dis202642778543PubTator, text miningPubMed
Activation-induced cytidine deaminase sustains glycolytic flux through MYST1 acetyltransferase-dependent lactylation in hepatocellular carcinoma.J Biol Chem202642772567PubTator, text miningPubMed
A USP28-BRD4 axis contributes to the acceleration of breast cancer growth by hyperglycemia.Cell Rep202642771521PubTator, text miningPubMed
Coordination-Driven Programming of MOF Stability via Targeting Protein Corona Engineering for Hypoxia-Relieving Sonodynamic Therapy.Biomacromolecules202642734277PubTator, text miningPubMed
MMSDH facilitates ACSL4 propionylation to counteract ferroptosis upon hypoxia and impairs PDAC chemotherapy efficacy.Nat Cancer202642728394PubTator, text miningPubMed
Lewis Acid-Mediated Interfacial Microenvironment Engineering for Enhanced Cathodic Electrochemiluminescence Aptasensing of Perfluorooctanoic Acid Based on Ligand Defect-Modulated MIL-88B(Fe) MOF.ACS Sens202642691483PubTator, text miningPubMed
Ca-BPDC Immobilization Redistributes Regional Proteolytic Preference of Serine Proteases.ACS Appl Bio Mater202642690895PubTator, text miningPubMed

1 to 10 of 2,655

See all 2,655 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/84148

GET https://conductscience.org/api/genes/v1/84148/patents?page=2