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Gene · 84152

PPP1R1B: protein phosphatase 1 regulatory inhibitor subunit 1B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PPP1R1B: protein phosphatase 1 regulatory inhibitor subunit 1B. Genes, record 84152. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84152

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Gene

Symbol
PPP1R1B
HGNC
Name
protein phosphatase 1 regulatory inhibitor subunit 1B
HGNC
NCBI Gene ID
84152
NCBI Gene
HGNC ID
HGNC:9287
HGNC
Ensembl
ENSG00000131771
NCBI Gene
Aliases
DARPP-32, DARPP32, FLJ20940
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UD71Protein phosphatase 1 regulatory subunit 1B2040Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 11564998 B22023-01-314831Q9UD71Espacenet
US 11564998 B22023-01-315921Q9UD71Espacenet
US 11446398 B22022-09-2068521Q9UD71Espacenet
US 11446398 B22022-09-2068524Q9UD71Espacenet
JP 2022524081 A2022-04-27171492Q9UD71Espacenet
JP 2022524081 A2022-04-27171495Q9UD71Espacenet
US 11078247 B22021-08-038837Q9UD71Espacenet
JP 2021018154 A2021-02-15750Q9UD71Espacenet
JP 2020062004 A2020-04-231404Q9UD71Espacenet
WO 2020043864 A12020-03-051923Q9UD71Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,656

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePPP1R1B papersNewest fiscal year
P30DK058404Molecular and Cellular Basis for Digestive Diseases102025
P30CA068485Cancer Center Support Grant92025
R01NS100529Identifying Factors Regulating Medium Spiny Neuron Differentiation or Maintenance as Therapeutic Targets for Huntington's Disease using Induced Pluripotent Stem Cells82025
P30CA033572Cancer Center Support Grant72025
P51OD011132Emory National Primate Research Center62025
P30DA018343Yale/NIDA Neuroproteomics Center52025
R01DA007359Molecular Studies of Cocaine Action in Brain52025
T32AG000266Training in Basic Research on Aging and Age-Related Disease52025
P30CA016672Cancer Center Support Grant42025
P30CA062203Cancer Center Support Grant42025

1 to 10 of 1,656Source NIH's project files

See all 1,656 nih grants

Papers1,720

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction to 'Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) maintains muscle progenitor identity by stabilizing the Ppp1r1b-lncRNA-PRC2 complex'.Nucleic Acids Res202642773871PubTator, text miningPubMed
Mendelian Randomization and Single-Cell Transcriptomic Analyses Implicate PPP1R1B as a Risk Factor of Intrahepatic Cholangiocarcinoma.Genes (Basel)202642650061PubTator, text miningPubMed
Current landscape and future perspectives of small-molecule therapeutics for Huntington's disease: From rational design to clinical translation.Eur J Med Chem202642617409PubTator, text miningPubMed
MetaOmixTools: A User-Friendly Web Suite for Meta-analysis of Ranked Features and Functional Enrichment.Comput Struct Biotechnol J202642614712PubTator, text miningPubMed
Do common dopaminergic variants modulate processing speed in cognitive aging? A longitudinal candidate gene study.PLoS One202642467707PubTator, text miningPubMed
iPSC Neurodegenerative Disease Initiative isogenic CAG repeat iPSC line for Huntington's disease.bioRxiv202642427629PubTator, text miningPubMed
Morphine Dependence Vaccines: Advances, Challenges, and Future Directions.Curr Pharm Biotechnol202642157589PubTator, text miningPubMed
Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) maintains muscle progenitor identity by stabilizing the Ppp1r1b-lncRNA-PRC2 complex.Nucleic Acids Res202642152677PubTator, text miningPubMed
The neuroanatomy and connectivity of the ventral striatum and ventral capsule area in the Göttingen minipig.Brain Struct Funct202642133082PubTator, text miningPubMed
Huntington's disease human lateral ganglionic eminence precursors differentiate into functionally mature medium spiny neurons exhibiting pathology.Stem Cells202642090468PubTator, text miningPubMed

1 to 10 of 1,720

See all 1,720 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/84152

GET https://conductscience.org/api/genes/v1/84152/patents?page=2