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NR0B2: nuclear receptor subfamily 0 group B member 2

1 protein, 24 patents, 0 drugs, 0 trials, 3,504 NIH grants and 6,444 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNR0B2HGNC
Namenuclear receptor subfamily 0 group B member 2HGNC
NCBI Gene ID8431NCBI Gene
HGNC IDHGNC:7961HGNC
EnsemblENSG00000131910NCBI Gene
AliasesSHP, SHP1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q15466Nuclear receptor subfamily 0 group B member 225714Ensembl, GeneID, HGNCUniProt

Patents 24

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1456140Q15466Espacenet
JP 2025147176 A2025-10-0615414Q15466Espacenet
JP 2025121934 A2025-08-204Q15466Espacenet
JP 2025028160 A2025-02-2815414Q15466Espacenet
KR 1020250010750 A2025-01-2115414Q15466Espacenet
JP 2024109657 A2024-08-1415253Q15466Espacenet
US 11732240 B22023-08-2288Q15466Espacenet
JP 2022551987 A2022-12-1426Q15466Espacenet
US 11446398 B22022-09-2058381Q15466Espacenet
JP 2022524081 A2022-04-27161352Q15466Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3504

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant202,025NIH's project files
P30CA016672Cancer Center Support Grant182,025NIH's project files
ZIABC005562Xenobiotic receptors112,025NIH's project files
P30DK034989Yale Liver Center102,025NIH's project files
R01DK113080Understanding Mechanisms that Regulate Liver Growth and Function102,025NIH's project files
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)92,025NIH's project files
T32ES007148Training in Environmental Toxicology92,025NIH's project files
P30CA016058Cancer Center Support Grant82,025NIH's project files
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged82,025NIH's project files
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers82,025NIH's project files

Papers 6444

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825856PubTator, text miningPubMed
42808596PubTator, text miningPubMed
42753699PubTator, text miningPubMed
42722135PubTator, text miningPubMed
42713544PubTator, text miningPubMed
42706011PubTator, text miningPubMed
42702174PubTator, text miningPubMed
42699277PubTator, text miningPubMed
42677839PubTator, text miningPubMed
42640491PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license