ConductScience.org, home

Gene · 8434

RECK: reversion inducing cysteine rich protein with kazal motifs

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. RECK: reversion inducing cysteine rich protein with kazal motifs. Genes, record 8434. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8434

On this page

Gene

Symbol
RECK
HGNC
Name
reversion inducing cysteine rich protein with kazal motifs
HGNC
NCBI Gene ID
8434
NCBI Gene
HGNC ID
HGNC:11345
HGNC
Ensembl
ENSG00000122707
NCBI Gene
Aliases
ST15, hRECK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95980Reversion-inducing cysteine-rich protein with Kazal motifs9711Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026219982 A12026-10-226O95980Espacenet
WO 2026219984 A12026-10-226O95980Espacenet
WO 2026219985 A12026-10-226O95980Espacenet
WO 2026219987 A12026-10-226O95980Espacenet
WO 2026219989 A12026-10-226O95980Espacenet
WO 2026220051 A12026-10-226O95980Espacenet
EP 4650780 A22025-11-199987O95980Espacenet
EP 4641201 A22025-10-2910261O95980Espacenet
JP 2025529142 A2025-09-043686O95980Espacenet
US 12371689 B22025-07-293686O95980Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants861

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRECK papersNewest fiscal year
IK6BX004016BLRD Research Career Scientist Award Application82025
P30CA016672Cancer Center Support Grant52025
R01HL070241Insulin-Like Growth Factor-1 and Atherosclerosis52025
I01BX003271Hepatic eNOS in the regulation of NASH42025
P30CA016058Cancer Center Support Grant42025
I01BX005845RECK in Adverse Cardiac Remodeling and Heart Failure32025
P30CA006973Regional Oncology Research Center32025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)32025
R01DK130243RECK regulation of NASH and fibrosis32025
P30CA008748Cancer Center Support Grant22025

1 to 10 of 861Source NIH's project files

See all 861 nih grants

Papers1,933

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
6PPDQ Promotes Cutaneous Squamous Cell Carcinoma Growth with PI3K-Akt/MMP9 Activation: Evidence from Integrated Network Toxicology and Experimental Investigation.Int J Mol Sci202642794731PubTator, text miningPubMed
Prevalence, Molecular Characterisation and Zoonotic Potential of Blastocystis sp. in Humans and Domestic Animals: A Cross-Sectional Study From Northeastern Iran.Trop Med Int Health202642444081PubTator, text miningPubMed
Functional interaction between miR-505-3p and miR-21 contributes to GBM suppression.Sci Rep202642350583PubTator, text miningPubMed
The Role of miRNA-21 in the Metastasis of Hepatocellular Carcinoma as a Therapeutic Target.Int J Hematol Oncol Stem Cell Res202642293239PubTator, text miningPubMed
Unraveling the Predictive Value of HGF, RECK, CYP1B1, and ZEB2 for Cancer Stemness and Immune Microenvironment in Pancreatic Adenocarcinoma.Stem Cells Int202642147787PubTator, text miningPubMed
A Pragmatic Approach Towards the Molecular Mechanisms of Dexamethasone induced Insulin Resistance and Diabetes Mellitus.Recent Adv Inflamm Allergy Drug Discov202642136448PubTator, text miningPubMed
Role of the WNT signalling pathway in physiological and pathological blood-brain barrier.Ann Med202642007489PubTator, text miningPubMed
Promoter hypomethylation of CDH7: a novel epigenetic marker associated with cerebral small vessel disease.Front Genet202641890232PubTator, text miningPubMed
Advances in the biological functions of miR‑205 in various diseases (Review).Mol Med Rep202641860043PubTator, text miningPubMed
[Matrix metalloproteinases in pituitary adenoma invasiveness].Probl Endokrinol (Mosk)202641834597PubTator, text miningPubMed

1 to 10 of 1,933

See all 1,933 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8434

GET https://conductscience.org/api/genes/v1/8434/patents?page=2