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Gene · 84444

Papers2,742

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

121 to 140 of 2,742

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TitleJournalYearPMIDFound bySource
Keep calm and reboot - how cells restart transcription after DNA damage and DNA repair.FEBS Lett202538991979PubTator, text miningPubMed
Correction: Regulation of the DNA Damage Response and Gene Expression by the Dot1L Histone Methyltransferase and the 53Bp1 Tumour Suppressor.PLoS One202439693380PubTator, text miningPubMed
Synergistic Strategies for KMT2A-Rearranged Leukemias: Beyond Menin Inhibitor.Cancers (Basel)202439682203PubTator, text miningPubMed
Chromatin accessibility: biological functions, molecular mechanisms and therapeutic application.Signal Transduct Target Ther202439627201PubTator, text miningPubMed
Somatic mutational landscape reveals mutational signatures and significantly mutated genes of cancer immunotherapeutic outcome and sex disparities.Front Immunol202439555056PubTator, text miningPubMed
Systematic identification of therapeutic targets for coronary artery calcification: an integrated transcriptomic and proteomic Mendelian randomization.Front Cardiovasc Med202439526184PubTator, text miningPubMed
Combined inhibition of histone methyltransferases EZH2 and DOT1L is an effective therapy for neuroblastoma.Cancer Med202439501501PubTator, text miningPubMed
Correction: Geng et al. Intracellular Delivery of DNA and Protein by a Novel Cell-Permeable Peptide Derived from DOT1L. Biomolecules 2020, 10, 217.Biomolecules202439456273PubTator, text miningPubMed
DOT1L protects against podocyte injury in diabetic kidney disease through phospholipase C-like 1.Cell Commun Signal202439456056PubTator, text miningPubMed
Epigenetic therapies targeting histone lysine methylation: complex mechanisms and clinical challenges.J Clin Invest202439403928PubTator, text miningPubMed
DOT1L: orchestrating methylation-dependent radiotheRAPy responses via BRCA1.Trends Pharmacol Sci202439389815PubTator, text miningPubMed
Dexamethasone Inhibits the Growth of B-Lymphoma Cells by Downregulating DOT1L.Cancer Rep (Hoboken)202439307938PubTator, text miningPubMed
Design, synthesis, and biological evaluation of adenosine derivatives targeting DOT1L and HAT as anti-leukemia agents.Bioorg Chem202439299178PubTator, text miningPubMed
The spread of chemical biology into chromatin.J Biol Chem202439276931PubTator, text miningPubMed
Extrapolating Lessons from Targeted Protein Degradation to Other Proximity-Inducing Drugs.ACS Chem Biol202439264973PubTator, text miningPubMed
Discovery of first-in-class DOT1L inhibitors against the R231Q gain-of-function mutation in the catalytic domain with therapeutic potential of lung cancer.Acta Pharm Sin B202439220866PubTator, text miningPubMed
SpikeFlow: automated and flexible analysis of ChIP-Seq data with spike-in control.NAR Genom Bioinform202439211331PubTator, text miningPubMed
DOT1L-mediated RAP80 methylation promotes BRCA1 recruitment to elicit DNA repair.Proc Natl Acad Sci U S A202439172790PubTator, text miningPubMed
Interplay between DOT1L and HDAC1 regulates Leishmania donovani infection in human THP-1 cells.Acta Trop202439103111PubTator, text miningPubMed
Pan‑cancer analysis on the role of KMT2C expression in tumor progression and immunotherapy.Oncol Lett202439091583PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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