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Gene · 8454

CUL1: cullin 1

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. CUL1: cullin 1. Genes, record 8454. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/8454

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
CUL1
HGNC
Name
cullin 1
HGNC
NCBI Gene ID
8454
NCBI Gene
HGNC ID
HGNC:2551
HGNC
Ensembl
ENSG00000055130
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13616Cullin-177648Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026063308 A2026-03-261Q13616Espacenet
EP 4650780 A22025-11-195686Q13616Espacenet
EP 4641201 A22025-10-295346Q13616Espacenet
US 12433888 B12025-10-0722Q13616Espacenet
JP 2025517969 A2025-06-125346Q13616Espacenet
JP 2025517970 A2025-06-125686Q13616Espacenet
EP 4555325 A22025-05-2122Q13616Espacenet
JP 2024123008 A2024-09-105688Q13616Espacenet
JP 2024123008 A2024-09-105689Q13616Espacenet
US 11884978 B22024-01-30483Q13616Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,806

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control312025
P30CA021765Cancer Center Support Grant (CCSG)302025
P30CA008748Cancer Center Support Grant232025
P30CA016672Cancer Center Support Grant222025
P30CA016087Cancer Center Support Grant182025
P30CA016086Cancer Center Support Grant132025
R01HL097376Sepsis-Associated Immune Suppression and F-box Proteins132025
R01HL096376E3 Ligase-Mediated Immunosuppression in Acute Lung Injury122025
R01DK095491Indole dysbiosis and mucosal inflammation102025
P30CA030199Cancer Center Support Grant (CCSG)92025

1 to 10 of 2,806Source NIH's project files

See all 2,806 nih grants

Papers4,328

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818077PubTator, text miningPubMed
42813898PubTator, text miningPubMed
42802181PubTator, text miningPubMed
42749721PubTator, text miningPubMed
42734152PubTator, text miningPubMed
42640714PubTator, text miningPubMed
42602184PubTator, text miningPubMed
42559520PubTator, text miningPubMed
42555346PubTator, text miningPubMed
42543005PubTator, text miningPubMed

1 to 10 of 4,328

See all 4,328 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8454

GET https://conductscience.org/api/genes/v1/8454/patents?page=2