Gene · 8456
FOXN1: forkhead box N1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FOXN1: forkhead box N1. Genes, record 8456. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8456
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15353 | Forkhead box protein N1 | 648 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents27
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4805378 A1 | 2026-09-16 | 632 | O15353 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 46554 | O15353 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 458 | O15353 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15006 | O15353 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 458 | O15353 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15006 | O15353 | Espacenet |
| JP 2025024198 A | 2025-02-19 | 12640 | O15353 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15006 | O15353 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14845 | O15353 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 32580 | O15353 | Espacenet |
1 to 10 of 27
See all 27 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,373
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FOXN1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 21 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 10 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 8 | 2025 |
| P01AG052359 | Thymic and Peripheral Aspects of T Cell Aging and Rejuvenation | 7 | 2025 |
| ZIAAI001222 | Characterization of the cellular and molecular bases of inborn errors of immunity | 7 | 2025 |
| P01CA022443 | Molecular Biology and Genetics of Human Tumor Viruses | 6 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 6 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,373Source NIH's project files
See all 1,373 nih grantsPapers1,428
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| METTL1-mediated m7G modification regulates hair follicle cycle via the HOXC13/FOXN1/DSG4 axis. | PLoS Genet | 2026 | 42771602 | PubTator, text mining | PubMed |
| Thymic regeneration and tumor immunotherapy. | Front Immunol | 2026 | 42712902 | PubTator, text mining | PubMed |
| Identification and Experimental Validation of Key Genes Related to Neuroendocrine in Periodontitis Based on Single-Cell and Bulk Transcriptome Data. | J Cell Mol Med | 2026 | 42634206 | PubTator, text mining | PubMed |
| Clinical rationale for thymic restoration in adult immunosenescence. | Immun Ageing | 2026 | 42415124 | PubTator, text mining | PubMed |
| Thymic cortical epithelial Psmb11-encoded β5t in mouse and human. | Int Immunol | 2026 | 42261593 | PubTator, text mining | PubMed |
| Injectable polysaccharide-based hydrogel delivering Poria cocos extracellular vesicles promotes hair regeneration in androgenetic alopecia via Wnt/β-catenin signaling. | Int J Biol Macromol | 2026 | 42142777 | PubTator, text mining | PubMed |
| Decision-Making Regarding the Administration of Live Vaccines to Patients With a FOXN1 Heterozygous Missense Variant. | Pediatr Int | 2026 | 42003786 | PubTator, text mining | PubMed |
| Autoreactive T cells and thymic atrophy pathway in thymic hyperplasia patients with myasthenia gravis. | Front Neurol | 2026 | 41948617 | PubTator, text mining | PubMed |
| Thymic epithelial tumors at the crossroads of immunity, autoimmunity, and immunotherapy. | Cancer Immunol Immunother | 2026 | 41843177 | PubTator, text mining | PubMed |
| Syndromic Inborn Errors of Immunity in TREC-Newborn Screening: 5-year Experience from the German Screening Program. | J Clin Immunol | 2026 | 41831046 | PubTator, text mining | PubMed |
1 to 10 of 1,428
See all 1,428 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8456
GET https://conductscience.org/api/genes/v1/8456/patents?page=2