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Gene · 8456

FOXN1: forkhead box N1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FOXN1: forkhead box N1. Genes, record 8456. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8456

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Gene

Symbol
FOXN1
HGNC
Name
forkhead box N1
HGNC
NCBI Gene ID
8456
NCBI Gene
HGNC ID
HGNC:12765
HGNC
Ensembl
ENSG00000109101
NCBI Gene
Aliases
FKHL20, RONU, TIDAND, TIDTA, TLIND, WHN
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15353Forkhead box protein N16482Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4805378 A12026-09-16632O15353Espacenet
JP 2026004568 A2026-01-1446554O15353Espacenet
EP 4641201 A22025-10-29458O15353Espacenet
JP 2025147176 A2025-10-0615006O15353Espacenet
JP 2025517969 A2025-06-12458O15353Espacenet
JP 2025028160 A2025-02-2815006O15353Espacenet
JP 2025024198 A2025-02-1912640O15353Espacenet
KR 1020250010750 A2025-01-2115006O15353Espacenet
JP 2024109657 A2024-08-1414845O15353Espacenet
US 11446398 B22022-09-2032580O15353Espacenet

1 to 10 of 27

See all 27 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,373

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFOXN1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant212025
P30CA016672Cancer Center Support Grant112025
P30CA068485Cancer Center Support Grant102025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant82025
P01AG052359Thymic and Peripheral Aspects of T Cell Aging and Rejuvenation72025
ZIAAI001222Characterization of the cellular and molecular bases of inborn errors of immunity72025
P01CA022443Molecular Biology and Genetics of Human Tumor Viruses62025
P30CA010815Consolidated Basic Cancer Research Program62025
P30CA016058Cancer Center Support Grant52025
P30CA046934University of Colorado Cancer Center Support Grant52025

1 to 10 of 1,373Source NIH's project files

See all 1,373 nih grants

Papers1,428

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
METTL1-mediated m7G modification regulates hair follicle cycle via the HOXC13/FOXN1/DSG4 axis.PLoS Genet202642771602PubTator, text miningPubMed
Thymic regeneration and tumor immunotherapy.Front Immunol202642712902PubTator, text miningPubMed
Identification and Experimental Validation of Key Genes Related to Neuroendocrine in Periodontitis Based on Single-Cell and Bulk Transcriptome Data.J Cell Mol Med202642634206PubTator, text miningPubMed
Clinical rationale for thymic restoration in adult immunosenescence.Immun Ageing202642415124PubTator, text miningPubMed
Thymic cortical epithelial Psmb11-encoded β5t in mouse and human.Int Immunol202642261593PubTator, text miningPubMed
Injectable polysaccharide-based hydrogel delivering Poria cocos extracellular vesicles promotes hair regeneration in androgenetic alopecia via Wnt/β-catenin signaling.Int J Biol Macromol202642142777PubTator, text miningPubMed
Decision-Making Regarding the Administration of Live Vaccines to Patients With a FOXN1 Heterozygous Missense Variant.Pediatr Int202642003786PubTator, text miningPubMed
Autoreactive T cells and thymic atrophy pathway in thymic hyperplasia patients with myasthenia gravis.Front Neurol202641948617PubTator, text miningPubMed
Thymic epithelial tumors at the crossroads of immunity, autoimmunity, and immunotherapy.Cancer Immunol Immunother202641843177PubTator, text miningPubMed
Syndromic Inborn Errors of Immunity in TREC-Newborn Screening: 5-year Experience from the German Screening Program.J Clin Immunol202641831046PubTator, text miningPubMed

1 to 10 of 1,428

See all 1,428 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8456

GET https://conductscience.org/api/genes/v1/8456/patents?page=2