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Gene · 84617

TUBB6: tubulin beta 6 class V

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TUBB6: tubulin beta 6 class V. Genes, record 84617. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84617

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Gene

Symbol
TUBB6
HGNC
Name
tubulin beta 6 class V
HGNC
NCBI Gene ID
84617
NCBI Gene
HGNC ID
HGNC:20776
HGNC
Ensembl
ENSG00000176014
NCBI Gene
Aliases
FPVEPD, HsT1601, MGC4083, TUBB-5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BUF5Tubulin beta-6 chain4460Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195209Q9BUF5Espacenet
EP 4641201 A22025-10-294791Q9BUF5Espacenet
JP 2025517969 A2025-06-124791Q9BUF5Espacenet
JP 2025517970 A2025-06-125209Q9BUF5Espacenet
US 11564998 B22023-01-315394Q9BUF5Espacenet
US 11446398 B22022-09-2093607Q9BUF5Espacenet
JP 2022524081 A2022-04-27196578Q9BUF5Espacenet
US 10463751 B22019-11-055394Q9BUF5Espacenet
JP 2018023373 A2018-02-1528121Q9BUF5Espacenet
JP 2017148049 A2017-08-3177Q9BUF5Espacenet

1 to 10 of 26

See all 26 patents

Drugs91

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABT-751CHEMBL20684Tubulin beta inhibitorINHIBITORChEMBL
AGS-16C3FCHEMBL4594455Tubulin disrupting agentDISRUPTING AGENTChEMBL
ANETUMAB RAVTANSINECHEMBL2109629Tubulin inhibitorINHIBITORChEMBL
ANG1005CHEMBL1089636Tubulin inhibitorINHIBITORChEMBL
ANVATABART OPADOTINCHEMBL4297892Tubulin inhibitorINHIBITORChEMBL
APRUTUMAB IXADOTINCHEMBL4650293Tubulin inhibitorINHIBITORChEMBL
ASG-5MECHEMBL2109574Tubulin inhibitorINHIBITORChEMBL
AVE-9633CHEMBL2109266Tubulin inhibitorINHIBITORChEMBL
AZINTUXIZUMAB VEDOTINCHEMBL4297859Tubulin inhibitorINHIBITORChEMBL
BELANTAMAB MAFODOTINCHEMBL4298209Tubulin inhibitorINHIBITORChEMBL

1 to 10 of 91

See all 91 drugs

Trials8,740

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604766PACLITAXELPHASE3ClinicalTrials.gov
NCT07602907PACLITAXELPHASE2ClinicalTrials.gov
NCT07601737PACLITAXELPHASE2ClinicalTrials.gov
NCT07601178PACLITAXELPHASE2ClinicalTrials.gov
NCT07599163PACLITAXELClinicalTrials.gov
NCT07595770PACLITAXELPHASE2ClinicalTrials.gov
NCT07594548PACLITAXELPHASE1ClinicalTrials.gov
NCT07591467DOCETAXELPHASE3ClinicalTrials.gov
NCT07589972VINORELBINEClinicalTrials.gov
NCT07588698VINCRISTINE SULFATEPHASE2ClinicalTrials.gov

1 to 10 of 8,740

See all 8,740 trials

NIH grants599

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTUBB6 papersNewest fiscal year
P30CA008748Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
R01GM094231COMPUTATIONAL TOOLS FOR MASS SPECTROMETRY-BASED INTERACTOME DATA32025
P30CA006973Regional Oncology Research Center22025
P30CA016058Cancer Center Support Grant22025
P30CA016086Cancer Center Support Grant22025
P50HD105351Boston Children's Hospital/HMS Intellectual and Developmental Disabilities Research Center22025
R01GM141109Mechanoregulation of Ciliary Motility22025
R01MH115957Scalable tool and comprehensive maps to interpret structural variation across the neuropsychiatric spectrum22025
R01NS058721ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders22025

1 to 10 of 599Source NIH's project files

See all 599 nih grants

Papers729

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Development and validation of cell-free RNA-based predictive models for preeclampsia using placental single-cell transcriptomic data.J Reprod Immunol202642623724PubTator, text miningPubMed
MIS12 Is Required for Kinetochore-Microtubule Attachment in Oocyte Meiosis.Adv Sci (Weinh)202642338338PubTator, text miningPubMed
Investigating the Function of C‑Terminal Tails of Human Tubulin Isotypes in the Motility Regulation of Cytoplasmic Dynein.ACS Omega202642179625PubTator, text miningPubMed
Overexpression of the erythropoietin receptor is associated with upregulation of tubulin beta 6 and paclitaxel resistance in ovarian adenocarcinoma cells.Acta Chim Slov202641918423PubTator, text miningPubMed
Genome-wide DNA methylation profiles and ribosomal DNA copy number at birth.Epigenetics202641774615PubTator, text miningPubMed
Detection for New Biomarkers of Tuberculosis Infection Activity Using Machine Learning Methods.Diseases202641745104PubTator, text miningPubMed
Single-cell analysis reveals the cellular and transcriptional heterogeneity of the normal pediatric thyroid.Front Endocrinol (Lausanne)202641727685PubTator, text miningPubMed
DRP1 depletion protects NK cells from hypoxia-induced dysfunction.Redox Rep202641706678PubTator, text miningPubMed
Expanding genetic and clinical spectra of β-tubulinopathies: A Korean study.J Hum Genet202641152456PubTator, text miningPubMed
Lactate metabolism orchestrates immune dysregulation in renal cancer: A multi-omics and causal inference study.Sci Prog202541406083PubTator, text miningPubMed

1 to 10 of 729

See all 729 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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