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Gene · 84634

KISS1R: KISS1 receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KISS1R: KISS1 receptor. Genes, record 84634. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84634

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Gene

Symbol
KISS1R
HGNC
Name
KISS1 receptor
HGNC
NCBI Gene ID
84634
NCBI Gene
HGNC ID
HGNC:4510
HGNC
Ensembl
ENSG00000116014
NCBI Gene
Aliases
AXOR12, CPPB1, GPR54, HH8, HOT7T175, KISS-1R
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q969F8KiSS-1 receptor3986Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025529142 A2025-09-042306Q969F8Espacenet
US 12371689 B22025-07-292306Q969F8Espacenet
US 12240915 B22025-03-0419Q969F8Espacenet
US 12150960 B22024-11-26119Q969F8Espacenet
JP 2024123008 A2024-09-106757Q969F8Espacenet
JP 2023002556 A2023-01-1019Q969F8Espacenet
US 11446398 B22022-09-2044481Q969F8Espacenet
US 11400116 B22022-08-027349Q969F8Espacenet
JP 2022531814 A2022-07-12202Q969F8Espacenet
JP 2022524081 A2022-04-27147452Q969F8Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants605

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKISS1R papersNewest fiscal year
R01HD082314Deciphering the functional role of MKRN3 in puberty and reproduction132025
T32DK007529Training Grant in Academic Endocrinology112025
P30CA168524The University of Kansas Cancer Center92025
P51OD011092Support for National Primate Research Center92025
T32HD007203Training in Reproductive Sciences92025
P30DK063491Diabetes Research Center (DRC)82025
P51OD011106Wisconsin National Primate Research Center Support72025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 542025
P30CA013148Comprehensive Cancer Center Support Grant32025
P30CA072720Cancer Center Support Grant32025

1 to 10 of 605Source NIH's project files

See all 605 nih grants

Papers1,760

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification and Functional Characteristics of NR5A1 Gene Variant in Patients with 46,XY Disorders of Sex Development.Genes (Basel)202642792964PubTator, text miningPubMed
Syndrome differentiation and treatment of pediatric central precocious puberty: role of the spleen-kidney axis.Front Immunol202642713456PubTator, text miningPubMed
Structural basis for Kisspeptin-10 selectivity toward KISS1R: computational insights.In Silico Pharmacol202642707558PubTator, text miningPubMed
Precocious puberty in boys: current insights into etiology, genetic advances, and environmental factors.Front Endocrinol (Lausanne)202642534783PubTator, text miningPubMed
Post-COVID-19 rise in central precocious puberty: an integrative Review.J Pediatr Endocrinol Metab202642515816PubTator, text miningPubMed
Kisspeptin as a Precision Biomarker in Personalized Pharmacy: Implications for Individualized Monitoring of Early Pregnancy Viability.Pharmacy (Basel)202642347060PubTator, text miningPubMed
Genetic analysis of three familial cases of pure terminal 19p13.3 duplication caused by maternal balanced translocation t(19;21) (p13.3;p12).Front Genet202642306095PubTator, text miningPubMed
Effects of Zearalenone on the Kiss1/GPR54 System and Related Genes Expression in the Hypothalamus and Pituitary Gland of Weaned Gilts.Toxins (Basel)202642188598PubTator, text miningPubMed
Kisspeptin-10 regulates glycosaminoglycan and decorin content in human cardiac fibroblast cultures.Pharmacol Rep202642159865PubTator, text miningPubMed
Case Report: Homozygous KISS1R mutation associated with congenital hypogonadotropic hypogonadism in two siblings: pulsatile GnRH therapy restores pituitary architecture and induces pubertal development.
Front Med (Lausanne)202642145763PubTator, text miningPubMed

1 to 10 of 1,760

See all 1,760 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/84634

GET https://conductscience.org/api/genes/v1/84634/patents?page=2