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Gene · 84649

DGAT2: diacylglycerol O-acyltransferase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DGAT2: diacylglycerol O-acyltransferase 2. Genes, record 84649. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84649

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Gene

Symbol
DGAT2
HGNC
Name
diacylglycerol O-acyltransferase 2
HGNC
NCBI Gene ID
84649
NCBI Gene
HGNC ID
HGNC:16940
HGNC
Ensembl
ENSG00000062282
NCBI Gene
Aliases
ARAT, GS1999FULL, HMFN1045
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96PD7Diacylglycerol O-acyltransferase 23880Ensembl, GeneID, HGNC

Source UniProt

Patents189

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12600978 B22026-04-14216Q96PD7Espacenet
JP 2026004568 A2026-01-1443724Q96PD7Espacenet
US 12486470 B22025-12-026Q96PD7Espacenet
EP 4650780 A22025-11-19695Q96PD7Espacenet
EP 4641202 A22025-10-2928Q96PD7Espacenet
US 12421523 B22025-09-236Q96PD7Espacenet
JP 2025529142 A2025-09-041250Q96PD7Espacenet
US 12371689 B22025-07-291250Q96PD7Espacenet
JP 2025517970 A2025-06-12695Q96PD7Espacenet
KR 1020250017231 A2025-02-0428Q96PD7Espacenet

1 to 10 of 189

See all 189 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,091

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDGAT2 papersNewest fiscal year
P30DK026743UCSF Liver Center112025
P30DK045735Yale Diabetes Research Center72025
P01CA097132Sphingolipids in Cancer Biology and Therapy52025
P30DK063491Diabetes Research Center (DRC)52025
UL1TR001863Yale Clinical and Translational Science Award52025
ZIABC005562Xenobiotic receptors52025
P30DK020572Michigan Diabetes Research Center (MDRC)42025
P30DK020593Vanderbilt Diabetes Research Center42025
P30CA068485Cancer Center Support Grant32025
P30CA093373Cancer Center Support Grant P3032025

1 to 10 of 1,091Source NIH's project files

See all 1,091 nih grants

Papers1,612

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Aryl hydrocarbon receptor-dependent lipid droplet accumulation supports redox homeostasis in hypoxia-induced PCa cells.Am J Cancer Res202642724686PubTator, text miningPubMed
Di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate upregulate PPARG and induce metabolic reprogramming in hepatocellular carcinoma cells: a pan-cancer and metabolomics study.Food Chem Toxicol202642674152PubTator, text miningPubMed
Lipid droplet dynamics control type I interferon responses and viperin expression to suppress viral replication.Vet Microbiol202642623889PubTator, text miningPubMed
Deletion of Pleiotrophin protects against high-fat diet-induced liver metabolic disease, independently of the sexual dimorphism in dietary response.Mol Biomed202642622926PubTator, text miningPubMed
CEBPB as a candidate mediator of DEGDB-induced tumor-associated phenotypes in colorectal cancer cells.Ecotoxicol Environ Saf202642617514PubTator, text miningPubMed
A pan-genome perspective uncovers the core genetic basis and evolutionary adaptation of lipid synthesis and vesicular transport in Nannochloropsis.J Phycol202642615245PubTator, text miningPubMed
Pharmacologic management of metabolic and alcohol-associated liver disease.Metab Target Organ Damage202642577825PubTator, text miningPubMed
DGAT2 inhibition in MASH: histologic promise and lipid paradox.Hepatobiliary Surg Nutr202642569416PubTator, text miningPubMed
Microglial checkpoint collapse in Alzheimer's disease: a tri-axial framework for biomarker-informed neuroimmune therapy.J Neuroinflammation202642393750PubTator, text miningPubMed
Dual IRE1 targets: Determinants of the cell fate?FEBS J202642298872PubTator, text miningPubMed

1 to 10 of 1,612

See all 1,612 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/84649

GET https://conductscience.org/api/genes/v1/84649/patents?page=2