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Gene · 8467

SMARCA5: SNF2 related chromatin remodeling ATPase 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SMARCA5: SNF2 related chromatin remodeling ATPase 5. Genes, record 8467. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8467

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Gene

Symbol
SMARCA5
HGNC
Name
SNF2 related chromatin remodeling ATPase 5
HGNC
NCBI Gene ID
8467
NCBI Gene
HGNC ID
HGNC:11101
HGNC
Ensembl
ENSG00000153147
NCBI Gene
Aliases
ISWI, SNF2H, WCRF135, hISWI, hSNF2H
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60264SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 51,05215Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465977O60264Espacenet
EP 4650780 A22025-11-193192O60264Espacenet
EP 4641201 A22025-10-292755O60264Espacenet
JP 2025147176 A2025-10-0615634O60264Espacenet
JP 2025517969 A2025-06-122755O60264Espacenet
JP 2025517970 A2025-06-123192O60264Espacenet
JP 2025028160 A2025-02-2815634O60264Espacenet
KR 1020250010750 A2025-01-2115634O60264Espacenet
JP 2024109657 A2024-08-1415473O60264Espacenet
US 11446398 B22022-09-2085396O60264Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,041

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSMARCA5 papersNewest fiscal year
P30CA008748Cancer Center Support Grant152025
R35GM127020ATP-dependent and independent mechanisms of regulating chromatin states72025
P30CA016058Cancer Center Support Grant52025
P30CA016672Cancer Center Support Grant52025
P30CA016087Cancer Center Support Grant42025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant42025
R01CA198279Shaping DNA Damage Response Networks Via Histone H2A Variants42025
R01EY012200Pax6 as a key regulator of lens development42025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202832025
P30CA091842Cancer Center Support Grant32025

1 to 10 of 1,041Source NIH's project files

See all 1,041 nih grants

Papers1,650

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction to: RSF-1/hSNF2H Promotes the Proliferation and Migration of Adenoid Cystic Cancer Cells.Bull Exp Biol Med202642799980PubTator, text miningPubMed
ISWI/CHRAC orchestrates sequential chromatin-remodeling activities by mobilizing DNA polymerase ε for homologous recombination.Commun Biol202642744936PubTator, text miningPubMed
Dysregulation of circ-SMARCA5, circ-RHOT1, and HNF1A and the association of HNF1A polymorphisms with hepatocellular carcinoma.Mol Biol Rep202642663735PubTator, text miningPubMed
Chromatin remodeling and epigenetic regulation of mesenchymal stem/stromal cells in osteoarthritis.Front Genet202642626673PubTator, text miningPubMed
GSDME acts as an epigenetic modifier to promote melanoma development via centriole biogenesis regulator PLK4.Cell Death Differ202642185629PubTator, text miningPubMed
Gasdermin C reprograms metabolism through the CAMKK2-AMPK axis to promote lung adenocarcinoma progression and radioresistance.Cell Rep202642176271PubTator, text miningPubMed
Correction to the article "RSF-1/hSNF2H Promotes the Proliferation and Migration of Adenoid Cystic Cancer Cells".Bull Exp Biol Med202642120794PubTator, text miningPubMed
RETRACTION: Circular RNA SMARCA5 May Serve as a Tumor Suppressor in Non-Small Cell Lung Cancer.J Clin Lab Anal202641972935PubTator, text miningPubMed
RSF-1/hSNF2H Promotes the Proliferation and Migration of Adenoid Cystic Cancer Cells.Bull Exp Biol Med202641949721PubTator, text miningPubMed
Vector semantics of multidomain protein architectures.Bioinform Adv202641938593PubTator, text miningPubMed

1 to 10 of 1,650

See all 1,650 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8467

GET https://conductscience.org/api/genes/v1/8467/patents?page=2