ConductScience.org, home

Gene · 8473

OGT: O-linked N-acetylglucosamine (GlcNAc) transferase

11 sourcesgene-search-2026-11-11-0.1.0

Download JSON
Cite this record

ConductScience Library. OGT: O-linked N-acetylglucosamine (GlcNAc) transferase. Genes, record 8473. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/8473

On this page

Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
OGT
HGNC
Name
O-linked N-acetylglucosamine (GlcNAc) transferase
HGNC
NCBI Gene ID
8473
NCBI Gene
HGNC ID
HGNC:8127
HGNC
Ensembl
ENSG00000147162
NCBI Gene
Aliases
FLJ23071, HINCUT-1, HRNT1, MGC22921, MRX106, O-GLCNAC, OGT1, XLID106
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15294UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit1,04644Ensembl, GeneID, HGNC

Source UniProt

Patents60

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1456524O15294Espacenet
EP 4650780 A22025-11-199362O15294Espacenet
EP 4641201 A22025-10-299606O15294Espacenet
EP 4620519 A22025-09-249O15294Espacenet
EP 4620520 A22025-09-249O15294Espacenet
EP 4620521 A22025-09-249O15294Espacenet
JP 2025517969 A2025-06-129606O15294Espacenet
JP 2025517970 A2025-06-129362O15294Espacenet
WO 2025093745 A12025-05-08266O15294Espacenet
US 12285484 B22025-04-29324O15294Espacenet

1 to 10 of 60

See all 60 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,643

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
ZIADK060103Enzymes of O-GlcNAc cycling linked to type-2 diabetes and neurodegeneration392025
ZIADK060101Targeted disruption the enzymes of O-GlcNAc cycling: Animal models of Disease352025
ZIADK060102Calmodulin-driven Nuclear Trafficking linked to diabetes and insulin signaling252025
P30CA008748Cancer Center Support Grant182025
P30CA016672Cancer Center Support Grant162025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant162025
R01GM121718Beyond the Active Site: Structure Informed Novel Regulatory Mechanisms and Functional Modulation of O-GlcNAc Transferase142025
UL1TR001863Yale Clinical and Translational Science Award132025
R01GM118847Cell signaling through O-GlcNAc reader proteins122025
R01GM125939Chemical Tools for the Investigation and Manipulation of Protein Glycosylation122025

1 to 10 of 2,643Source NIH's project files

See all 2,643 nih grants

Papers4,587

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42788889PubTator, text miningPubMed
42784431PubTator, text miningPubMed
42784112PubTator, text miningPubMed
42740582PubTator, text miningPubMed
42734649PubTator, text miningPubMed
42685690PubTator, text miningPubMed
42664701PubTator, text miningPubMed
42651138PubTator, text miningPubMed
42639309PubTator, text miningPubMed
42622529PubTator, text miningPubMed

1 to 10 of 4,587

See all 4,587 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8473

GET https://conductscience.org/api/genes/v1/8473/patents?page=2