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Gene · 84790

TUBA1C: tubulin alpha 1c

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TUBA1C: tubulin alpha 1c. Genes, record 84790. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84790

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Gene

Symbol
TUBA1C
HGNC
Name
tubulin alpha 1c
HGNC
NCBI Gene ID
84790
NCBI Gene
HGNC ID
HGNC:20768
HGNC
Ensembl
ENSG00000167553
NCBI Gene
Aliases
MGC10851, MGC14580, OZEMA24, TUBA6, bcm948
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BQE3Tubulin alpha-1C chain4490Ensembl, GeneID, HGNC

Source UniProt

Patents58

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194046Q9BQE3Espacenet
EP 4641202 A22025-10-294770Q9BQE3Espacenet
JP 2025517970 A2025-06-124046Q9BQE3Espacenet
KR 1020250017231 A2025-02-044770Q9BQE3Espacenet
JP 2023516705 A2023-04-20101Q9BQE3Espacenet
JP 2023516705 A2023-04-20102Q9BQE3Espacenet
US 11564998 B22023-01-315205Q9BQE3Espacenet
US 11446398 B22022-09-2093551Q9BQE3Espacenet
JP 2022524081 A2022-04-27196522Q9BQE3Espacenet
WO 2021175788 A12021-09-10101Q9BQE3Espacenet

1 to 10 of 58

See all 58 patents

Drugs90

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AGS-16C3FCHEMBL4594455Tubulin disrupting agentDISRUPTING AGENTChEMBL
ANETUMAB RAVTANSINECHEMBL2109629Tubulin inhibitorINHIBITORChEMBL
ANG1005CHEMBL1089636Tubulin inhibitorINHIBITORChEMBL
ANVATABART OPADOTINCHEMBL4297892Tubulin inhibitorINHIBITORChEMBL
APRUTUMAB IXADOTINCHEMBL4650293Tubulin inhibitorINHIBITORChEMBL
ASG-5MECHEMBL2109574Tubulin inhibitorINHIBITORChEMBL
AVE-9633CHEMBL2109266Tubulin inhibitorINHIBITORChEMBL
AZINTUXIZUMAB VEDOTINCHEMBL4297859Tubulin inhibitorINHIBITORChEMBL
BELANTAMAB MAFODOTINCHEMBL4298209Tubulin inhibitorINHIBITORChEMBL
BIIB-015CHEMBL2109575Tubulin inhibitorINHIBITORChEMBL

1 to 10 of 90

See all 90 drugs

Trials8,728

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604766PACLITAXELPHASE3ClinicalTrials.gov
NCT07602907PACLITAXELPHASE2ClinicalTrials.gov
NCT07601737PACLITAXELPHASE2ClinicalTrials.gov
NCT07601178PACLITAXELPHASE2ClinicalTrials.gov
NCT07599163PACLITAXELClinicalTrials.gov
NCT07595770PACLITAXELPHASE2ClinicalTrials.gov
NCT07594548PACLITAXELPHASE1ClinicalTrials.gov
NCT07591467DOCETAXELPHASE3ClinicalTrials.gov
NCT07589972VINORELBINEClinicalTrials.gov
NCT07588698VINCRISTINE SULFATEPHASE2ClinicalTrials.gov

1 to 10 of 8,728

See all 8,728 trials

NIH grants664

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTUBA1C papersNewest fiscal year
P30CA008748Cancer Center Support Grant72025
P20GM103446Delaware INBRE22025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA015704Cancer Center Support Grant22025
P30CA016672Cancer Center Support Grant22025
P30CA030199Cancer Center Support Grant (CCSG)22025
P30CA062203Cancer Center Support Grant22025
P30CA071789University of Hawaii Cancer Center CCSG22025
P50CA097186The Pacific Northwest Prostate Cancer SPORE22025
P50CA116201Mayo Clinic Breast Cancer SPORE22025

1 to 10 of 664Source NIH's project files

See all 664 nih grants

Papers852

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Machine learning identifies ac4C-related prognostic signature and TUBA1C as therapeutic target in COAD.Mamm Genome202642693326PubTator, text miningPubMed
Common Molecular Mechanisms and Candidate Drug Targets in Type 2 Diabetes Mellitus and Atherosclerotic Cardiovascular Disease.J Vis Exp202642612061PubTator, text miningPubMed
Proteomic and metabolomic analysis of human follicular fluid from follicles with different diameters.Front Cell Dev Biol202642597911PubTator, text miningPubMed
An externally validated lactylation-associated prognostic signature for overall survival prediction in lung adenocarcinoma identifies TUBA1C as a candidate gene.Transl Cancer Res202642591440PubTator, text miningPubMed
XGBoost-SHAP Interpretable Modeling Identifies and Validates an Eight-Gene Biomarker for Hepatic Encephalopathy Risk Prediction in Cirrhosis.Int J Mol Sci202642589578PubTator, text miningPubMed
Glycosylation-related gene risk model and functional validation of OSTC and TUBA1C in lung adenocarcinoma.Respir Res202642464299PubTator, text miningPubMed
Identification of potential vinorelbine-associated prognostic genes in breast cancer through integrative bioinformatics and experimental validation.Front Oncol202642434754PubTator, text miningPubMed
Machine learning-based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer.Oncol Lett202642027644PubTator, text miningPubMed
Lactate-Induced Lactylation Enhances BMAL1 Transcription and Nuclear Translocation, Promoting Bevacizumab Resistance in Glioblastoma through VEGFA.Clin Cancer Res202641995718PubTator, text miningPubMed
Transcriptional Modulation of Infertility-Associated Genes Following Chlamydia trachomatis Infection in Human Fallopian Tube Mesenchymal Cells: In Silico Study.Genes (Basel)202641898836PubTator, text miningPubMed

1 to 10 of 852

See all 852 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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