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Gene · 84823

LMNB2: lamin B2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LMNB2: lamin B2. Genes, record 84823. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/84823

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Gene

Symbol
LMNB2
HGNC
Name
lamin B2
HGNC
NCBI Gene ID
84823
NCBI Gene
HGNC ID
HGNC:6638
HGNC
Ensembl
ENSG00000176619
NCBI Gene
Aliases
EPM9, LAMB2, LMN2, MCPH27
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q03252Lamin-B26201Ensembl, GeneID, HGNC

Source UniProt

Patents13

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195701Q03252Espacenet
EP 4641202 A22025-10-294998Q03252Espacenet
JP 2025517970 A2025-06-125701Q03252Espacenet
KR 1020250017231 A2025-02-044998Q03252Espacenet
US 11773371 B22023-10-0326Q03252Espacenet
US 11446398 B22022-09-2044930Q03252Espacenet
JP 2022524081 A2022-04-27147901Q03252Espacenet
US 11078247 B22021-08-036259Q03252Espacenet
US 10155008 B22018-12-184Q03252Espacenet
WO 2018138478 A12018-08-0226Q03252Espacenet

1 to 10 of 13

See all 13 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants923

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLMNB2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant112025
ZIABC010411Initiation of DNA Replication in Mammalian Cells72025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025
P30CA010815Consolidated Basic Cancer Research Program42025
P30CA016086Cancer Center Support Grant42025
ZIABC010309Nuclear Architecture and Disease42025
ZIAHG200305Hutchinson-Gilford Progeria syndrome--a model for the genetics of aging.42025
P20GM103432Wyoming IDeA Networks for Biomedical Research Excellence Phase 432025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
P30CA023168Cancer Center Support Grant32025

1 to 10 of 923Source NIH's project files

See all 923 nih grants

Papers1,344

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Lamin B1 coordinates the assembly of the nuclear lamina.J Cell Sci202642781858PubTator, text miningPubMed
Identification of disulfidptosis-related molecular subtypes in pleural mesothelioma demonstrates a correlation with the immune infiltration, prognosis and therapy efficacy.Discov Oncol202642627616PubTator, text miningPubMed
Combinatorial post-translational modification reprogramming of the endomembrane system in colorectal cancer.Transl Cancer Res202642445424PubTator, text miningPubMed
Identification of GADD45B, HMGB3, LMNB2, and MFAP5 as lactylation-related prognostic markers for survival prediction in esophageal cancer.Transl Cancer Res202642445420PubTator, text miningPubMed
Common pathogenic mechanisms in the hippocampus across neurodegenerative dementias: Alzheimer's disease, Down syndrome, and Parkinson's disease.NPJ Dement202642078116PubTator, text miningPubMed
Integrative Bioinformatic Analysis Identifies Key Genes Driving Breast Cancer Brain Metastasis.Diagnostics (Basel)202642072775PubTator, text miningPubMed
Retraction: miR-122 Inhibits Hepatocarcinoma Cell Progression by Targeting LMNB2.Oncol Res202642065077PubTator, text miningPubMed
Tau oligomerization induces nuclear lamina invagination and chromatin remodeling in Alzheimer's disease.Acta Neuropathol202642017968PubTator, text miningPubMed
LMNB2 promotes prostate cancer progression and epithelial-mesenchymal transition via the Wnt/β-catenin pathway.Discov Oncol202642012624PubTator, text miningPubMed
Nuclear Lamins: A Molecular Bridge Coupling Extracellular Mechanical Cues to Intranuclear Signal Transduction and Gene Regulation.Int J Mol Sci202641977436PubTator, text miningPubMed

1 to 10 of 1,344

See all 1,344 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/84823

GET https://conductscience.org/api/genes/v1/84823/patents